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BioWorld - Saturday, May 16, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Origenis, Oncobone partner for cancer bone metastasis assets

Nov. 25, 2024
Oncobone Ventures Ltd. and Origenis GmbH have signed a framework agreement to develop novel therapies targeting cancer bone metastasis. Origenis leverages its artificial intelligence (AI)-driven technology platform Molmind-Moresystem-Brainstorm to design innovative targeted small-molecule therapies.
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Immuno-oncology

CO-005 is potent new anti-CD47 fusion protein

Nov. 25, 2024
Researchers from Caedo Oncology AS presented the discovery and preclinical characterization of CO-005, a novel anti-CD47 fusion protein being developed for the treatment of lymphoma.
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3D rendering of drug linked to antibody
Immuno-oncology

Series B financing at Adcendo to fund ADC pipeline

Nov. 25, 2024

Adcendo ApS has closed an oversubscribed $135 million series B financing round to support its development of first-in-class antibody-drug conjugates (ADCs) for the treatment of cancers with a high unmet medical need.


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Frank Borriello, CEO, Alloplex
Newco news

Alloplex’s Suplexa reawakens immune cells to fight cancer

Nov. 25, 2024
By Tamra Sami
When it comes to cell therapy, Alloplex Biotherapeutics Inc. CEO Frank Borriello said he believes that autologous, personalized therapy is the only thing that makes sense. “The allure of an off-the-shelf therapy has been such a magnet. It sucked in a lot of companies into that dream, and I'm sorry to say, it hasn't really worked out for them,” he told BioWorld. Instead, Borriello said he envisioned a cell training platform that doesn’t just tweak a single immune pathway but instead harnesses multiple immune pathways to turn the tables on cancer.
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Illustration of gut bacteria on scales being evaluated by AI chip
Gastrointestinal

Machine learning links microbiome composition to bacterial load

Nov. 22, 2024
By Mar de Miguel
Many studies have linked the presence of specific bacteria to various diseases. But a general overgrowth of gut bacteria can be a symptom of different conditions, including colorectal cancer and inflammatory bowel disease.
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Breast cancer illustration
Cancer

Therabene molecules show promise in triple-negative breast cancer model

Nov. 22, 2024
Therabene Inc. has released promising preclinical results for two new novel molecules targeting aggressive cancers.
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Cancer

GSC-002639 shows antitumor efficacy against PIK3CA-mutant tumors

Nov. 22, 2024
Mutations in the PIK3CA gene are present in about 4% to 36% of cancers such as breast, ovarian, endometrial and colorectal cancer, among others.
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Immuno-oncology

BB-203, a potentially best-in-class anti-PD-L1/anti-VEGF VHH bispecific antibody

Nov. 22, 2024
Bright Biologics LLC reported the discovery and preclinical evaluation of BB-203, an anti-PD-L1/anti-VEGF bispecific antibody (Ab) being developed for the treatment of cancer.
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Immuno-oncology

B7-H3/CD28 bispecific antibody enhances T-cell engager immunotherapies

Nov. 22, 2024
Researchers from Xencor Inc. described the preclinical characterization of XmAb-808.
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Molecule illustration
Cancer

Transposon Therapeutics acquires nucleoside analogues for cancer from Primefour

Nov. 22, 2024
Transposon Therapeutics Inc. has acquired a portfolio of novel nucleoside analogues from Primefour Therapeutics Inc. for the targeted treatment of pancreatic cancer, certain other solid tumors and hematologic cancers.
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