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BioWorld - Friday, May 15, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Deal illustration

Genexine, EPD Biotherapeutics to merge for new protein degraders

July 5, 2024
By Marian (YoonJee) Chu
Seoul, South Korea-based Genexine Co. Ltd. plans to merge with privately held EPD Biotherapeutics Co. Ltd. by October 2024 to build a pipeline of novel targeted protein degradation therapeutics with EPD Bio’s BioPROTAC platform technology.
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B-cell releasing antibodies

Engineered plasma cells produce effective bispecific antibodies against leukemia

July 5, 2024
By Mar de Miguel
Scientists at the University of Washington have engineered human plasma B cells modified to express long-lasting bispecific antibodies that could be used to treat leukemia without requiring continuous dosing.
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DNA mutations or genetic disorder concept art

Researchers identify thousands of high-risk cancer gene variants

July 5, 2024
By Holland Johnson
Researchers from the Wellcome Sanger Institute, and their collaborators at The Institute of Cancer Research, London and the University of Cambridge assessed the health impact of all possible genetic changes in the tumor protection gene, BRCA1-associated protein 1 gene.
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Serac Imaging Systems Seracam

Serac sees encouraging data from trials with gamma imaging camera

July 5, 2024
By Shani Alexander
Serac Imaging Systems Ltd. is seeing encouraging results from ongoing trials at three sites, which are comparing its Seracam portable hybrid gamma-optical camera for medical imaging to standard of care nuclear medicine imaging, Mark Rosser, CEO of the company, told BioWorld.
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GeneType-test

Genetic Technologies’ Genetype test detects early risk for multiple diseases

July 5, 2024
By Tamra Sami
Nearly 80% of people in Australia and the U.S. that used Genetic Technologies Ltd.’s Genetype multi-risk assessment test showed an elevated risk for at least one disease covered by the test.
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Cancer

New GTPase KRAS inhibitors disclosed in Risen Pharma patent

July 5, 2024
Researchers at Risen (Shanghai) Pharma Eng Co. Ltd. and Risen (Suzhou) Pharma Tech Co. Ltd. have divulged GTPase KRAS inhibitors reported to be useful for the treatment of cancer.
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Illustration of cancer tumor on pancreas
Cancer

XPO1 as a therapeutic target in pancreatic neuroendocrine tumors

July 5, 2024
Researchers from the National Cancer Institute presented data from a study that aimed to explore the role of the major nuclear exporter protein exportin 1 (XPO1) in pancreatic neuroendocrine tumor (pNET) subsistence and therapy resistance.
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Brain tumor illustration
Immuno-oncology

STING agonist exerts robust preclinical antitumor activity in glioma models

July 5, 2024
Activation of the stimulator of interferon genes (STING) pathway has recently proven effective as an antiproliferative strategy in glioma and melanoma.
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Child drawing with pencil
Biomarkers

NKX3.1 identified as a prognostic marker in pediatric craniopharyngioma

July 5, 2024
Craniopharyngiomas are a rare brain cancer of the suprasellar region, and despite being benign tumors, their management can be challenging. Investigators from the Children’s Hospital of Philadelphia have aimed to identify transcriptional factors that may predict recurrence of craniopharyngiomas.
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Cancer

Betta Pharmaceuticals describes new GTPase KRAS mutant degradation inducers

July 4, 2024
Betta Pharmaceuticals Co. Ltd. has identified proteolysis targeting chimera (PROTAC) compounds comprising a Von Hippel-Lindau disease tumor suppressor (VHL) ligase binding moiety to pan GTPase KRAS (mutant) binding moiety through a linker reported to be useful for the treatment of cancer.
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