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BioWorld - Saturday, February 21, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Antibody-drug conjugate illustration

Biotheus, Hansoh ink potential ¥5B deal for new bispecific ADCs

March 18, 2024
By Marian (YoonJee) Chu
Chinese biotechs Biotheus Inc. and Hansoh Pharmaceutical Group Co. Ltd. partnered again under a new potential ¥5 billion (US$698.98 million) deal to develop bispecific antibody-drug conjugates (BsADCs), using Biotheus’ EGFR-cMet bispecific antibody.
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Elekta ProKnow

NICE taking a close look at Elekta’s Proknow systems

March 18, 2024
By Mark McCarty
The U.K. National Institute for Health and Care Excellence (NICE) has released a preliminary health technology assessment for three modules of the Proknow series of software systems by Stockholm-based Elekta AB, which may improve the delivery of radiotherapy services across the U.K. However, NICE indicated it wants to see more evidence regarding the impact of these software modules on radiotherapy treatment plans.
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Brain cancer illustration
Cancer

First dual EZH2/HSP90 inhibitor against glioblastoma reported

March 18, 2024
Scientists at Taipei Medical University in Taiwan have developed a compound that could prevent resistance to temozolomide in the chemical treatment of glioblastoma.
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Cancer

Shanghai Allist Pharmaceuticals identifies GTPase KRAS inhibitors for cancer

March 18, 2024
Shanghai Allist Pharmaceuticals Co. Ltd. has patented nitrogen-containing heterocyclic compounds acting as GTPase KRAS, particularly G12D or G12V mutant, inhibitors reported to be useful for the treatment of cancer.
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Cancer

Merck KGaA patent describes KIFC1 inhibitors for cancer

March 18, 2024
Merck KGaA has identified substituted bicycles acting as kinesin-like protein KIFC1 inhibitors potentially useful for the treatment of cancer.
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Immuno-oncology

Abbvie discloses anti-SEZ6 antibody-drug conjugates

March 18, 2024
Abbvie Inc. has prepared and tested new antibody-drug conjugates comprising an antibody targeting seizure protein 6 homolog (SEZ6) covalently linked to DNA topoisomerase I inhibitors through a linker.
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Dendritic cells
Cancer

Asgard’s ‘direct reprogramming strategy’ garners €30M series A

March 18, 2024
By Nuala Moran
Asgard Therapeutics AB has raised €30 million (US$32.8 million) in a series A round to advance a novel approach to cancer immunotherapy, in which it is proposed to reprogram cancer cells into functional antigen-presenting dendritic cells in vivo, activating a host immune response against the tumor.
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FDA approved icons and medical professional

BMS and Mirum add approvals to established drugs

March 15, 2024
By Lee Landenberger
Two sNDAs, one from Bristol Myers Squibb Co. (BMS) and the other from Mirum Pharmaceuticals Inc., have received U.S. FDA approval to further expand their treatment indications.
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Medical Korea 2024

Proton, heavy ion radiotherapy centers on rise: Medical Korea 2024

March 15, 2024
By Marian (YoonJee) Chu
Medical Korea 2024 opened to a large audience in Seoul, South Korea for a two-day run to highlight advances in the medical field, including those in radiotherapy.
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Esophageal cancer

FDA clears Beigene’s PD-1 inhibitor Tevimbra in esophageal cancer

March 15, 2024
By Tamra Sami
The U.S. FDA has approved Beigene Co. Ltd.’s Tevimbra (tislelizumab-jsgr) as a monotherapy for treating adults with unresectable or metastatic esophageal squamous cell carcinoma following prior chemotherapy that did not include a PD-1 inhibitor. A humanized IgG4 anti-PD-1 monoclonal antibody, tislelizumab is designed to minimize binding to Fc-gamma receptors on macrophages, helping to aid the body’s immune cells to detect and fight tumors.
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