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BioWorld - Tuesday, May 19, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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Cancer

Gilead Sciences patents new CD73 inhibitors for cancer

Jan. 25, 2024
Gilead Sciences Inc. has disclosed 5'-nucleotidase (CD73) inhibitors reported to be useful for the treatment of cancer.
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Cancer

MDM2 inhibitor shows efficacy in wild-type p53 cancer models

Jan. 25, 2024
Researchers from the Chinese Academy of Sciences and collaborators reported on the discovery and preclinical characterization of JN-122, a potent spiroindoline derivative that showed a Ki value of 0.7 nM against MDM2.
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Cancer cell destruction by nanoparticles
Cancer

Nanoparticle co-delivery of TGF-β and COX-2 siRNAs shows efficacy in vivo

Jan. 25, 2024
Researchers from Sirnaomics Inc. presented preclinical evaluation of novel intravenous polypeptide nanoparticle designed to simultaneously deliver two siRNAs, silencing TGF-β and COX-2.
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Cancer

ACSS2 is target for pancreatic neuroendocrine tumors

Jan. 25, 2024
Pancreatic neuroendocrine neoplasms (pNENs) are rare tumors that arise from neuroendocrine cells.
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Structure of human CD47 (violet) in complex with human SIRP alpha (green)
Immuno-oncology

Biosion's anti-SIRPα antibody BSI-082 cleared to enter clinic

Jan. 25, 2024
Biosion Inc. has gained FDA clearance of its IND application for BSI-082, a novel anti-SIRPα monoclonal antibody (mAb) candidate.
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Cancer

Synnovation Therapeutics launches with $102M series A

Jan. 25, 2024
Synnovation Therapeutics Inc. has launched with a $102 million series A financing.
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Cancer cells
Immuno-oncology

Cytomx receives IND clearances for CX-2051 and CX-801

Jan. 25, 2024
Cytomx Therapeutics Inc. has received clearances from the FDA for IND applications for two conditionally activated Probody therapeutics.
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Test tubes with blood samples
Immune

With series A funds, IMU Bio’s Cytatlas identifies cell types and immune signatures

Jan. 24, 2024
By Nuala Moran
IMU Biosciences Ltd. has raised £11.5 million (US$14.7 million) in a series A round to further develop and commercialize profiling technology that can identify from a blood sample which of more than 2,000 cell types are present in an individual’s immune system.
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Test tubes with blood samples

With series A funds, IMU Bio’s Cytatlas identifies cell types and immune signatures

Jan. 24, 2024
By Nuala Moran
IMU Biosciences Ltd. has raised £11.5 million (US$14.7 million) in a series A round to further develop and commercialize profiling technology that can identify from a blood sample which of more than 2,000 cell types are present in an individual’s immune system.
Read More
Cancer

Relay Therapeutics presents new ERα degraders

Jan. 24, 2024
Relay Therapeutics Inc. has divulged proteolysis targeting chimeric (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety covalently linked to an estrogen receptor α (ERα; ESR1)-targeting moiety.
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