Kinimmune Inc. has received US$400,000 in funding from the National Cancer Institute (NCI) at the National Institutes of Health (NIH) for its phase I STTR application to advance the preclinical development of KIN-102, an immunostimulant for intratumoral injection that is designed to turn cold tumors hot for synergy with immuno-oncology drugs, such as checkpoint inhibitors.

Hamlet Pharma AB has shown that daily, long-term treatment with bovine α-lactalbumin made lethal to tumor cells (BAMLET) in drinking water inhibits intestinal tumor development in mice genetically susceptible to intestinal tumors, compared to mice not receiving BAMLET.

Researchers from Incyte Research Institute presented the discovery of a cyclin-dependent kinase 2 (CDK2) inhibitor, INCB-123667, being developed for the treatment of cyclin E dysregulated cancers.

Transcode Therapeutics Inc. has reported promising preclinical results with its immunotherapy candidate, TTX-siPDL1, in pancreatic adenocarcinoma.

A new method for controlling naturally magnetized bacteria has improved the prospects of applying them as vehicles for intratumoral delivery of cancer drugs and in hyperthermia therapy.

Shares in Clovis Oncology Inc. (NASDAQ:CLVS) tumbled more than 71% after it warned it is facing bankruptcy with barely enough cash left to last until the end of 2022, debts of more than $3 billion, and dwindling revenues from its only approved cancer drug, Rubraca (rucaparib).