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BioWorld - Saturday, February 7, 2026
Home » Topics » Disease categories and therapies » Cancer

Cancer
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PRMT5 targeting for the treatment of ER+/RB1-deficient breast cancer

Dec. 15, 2021

CHK1 loss promotes the antiproliferative activity of ERK inhibitors in KRAS-mutant PDAC

Dec. 15, 2021

RALA as a potential therapeutic target in TNBC

Dec. 15, 2021

BCL6 PROTAC degrader ARVN-71228 shows efficacy in preclinical models of DLBCL

Dec. 15, 2021

Panbela's SBP-101 shows preclinical promise for ovarian cancer

Dec. 15, 2021
Hand holding gear, dollar sign

Avistone raises $200M, acquires Pearl Biotech

Dec. 14, 2021
By Doris Yu
Avistone Biotechnology Co. Ltd. raised more than $200 million to support its oncology drug development and the acquisition Pearl Biotechnology Co. Ltd. with the aim of creating a “fully-integrated” targeted oncology platform. Vivo Capital LLC led the financing, with participation from Bain Capital LP. and Primavera Capital Group.
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Hong Kong stock market illustration

Canbridge raises $77.4M with Hong Kong IPO

Dec. 14, 2021
By David Ho
Canbridge Pharmaceuticals Inc. has raised HK$604 million ($77.4 million) with a listing on the Hong Kong stock exchange, selling about 56.3 million shares (1228.HK) at HK$12.18 per share. The shares fell to HK$8.90 at the close of trading Dec. 10. Almost half the funds will support advancement of Canbridge’s lead candidate, CAN-008, a glycosylated CD95-Fc fusion protein in phase II testing for glioblastoma, while another quarter will support other major pipeline programs.
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Green approved stamp

Henlius bevacizumab biosimilar receives China marketing approval

Dec. 14, 2021
By Doris Yu
Shanghai Henlius Biotech Inc.’s self-developed Hanbeitai (bevacizumab biosimilar) has received marketing approval from China’s NMPA.
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Doctor holding digital tablet with image of skull

Galera’s stock doubles after study correction

Dec. 14, 2021
By Lee Landenberger
The error in phase III data reported in late October that sank Galera Therapeutics Inc.’s stock  (NASDAQ:GRTX) has been corrected, prompting share values to nearly double on Dec. 14. The error, according to J. Mel Sorensen, Galera’s president and CEO, had resulted in a false “p” value, leading the company to report the study had failed to achieve statistical significance on its primary endpoint. He called the programming error that caused the confusion “quite subtle.”
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Immatics gets $150M up front as BMS licenses bispecific TCR program

Dec. 14, 2021
By Cormac Sheridan
DUBLIN – Immatics NV is banking $150 million up front and could earn up to $770 million more in development, regulatory and commercial milestones from a licensing deal with Bristol Myers Squibb Co. involving IMA-401, its lead bispecific engineered T-cell receptor (TCR).
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