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BioWorld - Saturday, April 11, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Farapulse

Farapulse bolsters Boston Scientific earnings

April 25, 2024
By Holland Johnson
In its first quarter earnings call, Boston Scientific Corp. reported 72% global sales growth in its electrophysiology division, for $300 million, bolstered by surging sales of its recently debuted Farapulse pulse field ablation system, which the company received U.S. FDA approval for in Janua.
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K DTx VIVIDBrain

Korea taps into AI, DTx boom with new approvals, investments

April 24, 2024
By Marian (YoonJee) Chu
South Korean med-tech companies Nunaps Co. Ltd. and Share & Service are the latest to clear domestic approvals for digital therapeutics as the government ramps up R&D funding for artificial intelligence-based medical technologies.
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Medically accurate illustration of a baby in the womb of a pregnant mother
Cardiovascular

Peripartum cardiomyopathy is associated with placental senescence

April 24, 2024
By Mar de Miguel
Scientists at Massachusetts General Hospital have linked the risk of heart failure during pregnancy and senescence proteins produced by placental aging, which could clarify how peripartum cardiomyopathy (PPCM) is triggered and opens the door to the development of cardiac function therapies in late pregnancy.
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Hand holding lightbulb
Cardiovascular

New York University patents new RAGE receptor antagonists

April 23, 2024
New York University has disclosed RAGE receptor antagonists reported to be useful for the treatment of cancer, SARS-CoV-2 infection (COVID-19), diabetic complications, ischemia reperfusion injury, neurodegeneration, obesity, and cardiovascular and inflammatory disorders, among others.
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Cardiovascular

Shanghai Institute of Materia Medica patents new compounds to treat arterial aneurysm

April 19, 2024
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences has disclosed compounds reported to be useful for the treatment of arterial aneurysm.
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Financial line graph

Abbott raises midpoint of yearly guidance, still sees stock slip

April 18, 2024
By Holland Johnson
Despite the bullish outlook in its quarterly earnings call, which included raising the midpoint of its full-year guidance range, Abbott Laboratories stock slipped on its light second-quarter outlook.
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Cardiovascular

Study investigates how PCSK9 leads to atherosclerosis progression independently of LDL receptor

April 18, 2024
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is highly expressed in adult hepatocytes. PCSK9 binds to and promotes the degradation of the low-density lipoprotein (LDL) receptor, thereby increasing LDL cholesterol levels. PCSK9 inhibition has emerged as a promising strategy for cardiovascular diseases. However, it is still unclear whether PCSK9 can trigger blood vessel inflammation directly modulating monocytes or endothelial cells independently of LDL receptor.
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Business people with hands atop a digital globe

J&J’s Duato says company to continue M&A surge

April 17, 2024
By Holland Johnson
As Johnson & Johnson's (J&J) first-quarter revenue missed Wall Street estimates for medical devices on April 16, CEO Joaquin Duato noted that the company will continue to look for major M&A plays to boost long-term growth in the wake of its recently reported $13.1 billion buy of Shockwave Medical Inc.
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1-10-abbott-heartmate3.png

Long-term use of Heartmate devices associated with obstruction

April 16, 2024
By Mark McCarty
The long-term use of ventricular assist devices is becoming a problem for at least some of these devices, as demonstrated by the recall of the Heartmate II and Heartmate 3 devices by Abbott Laboratories’ Abbott Vascular division due to obstruction of the outflow graft used to attach the device to the human heart.
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Ischemic stroke
Neurology/Psychiatric

Novel GluN2B-NMDAR antagonist demonstrates excellent safety and efficacy in MCAO rat model

April 15, 2024
Researchers from Hefei Industrial Pharmaceutical Institute Co. Ltd. published data detailing the design and biological evaluation of novel NMDAR-GluN2B antagonists as potential candidates for the treatment of ischemic stroke.
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