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BioWorld - Wednesday, July 1, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Human heart within crosshairs
Cardiovascular

Astrazeneca selects novel heart failure target from Benevolentai collaboration

May 15, 2024
Astrazeneca plc has added a novel target for heart failure to its discovery portfolio through its collaboration with Benevolentai Ltd.
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Heart with blocked arteries
Cardiovascular

Plaquetec and Babraham Institute demonstrate druggability of pro-inflammatory protein for coronary artery disease

May 15, 2024
A collaboration between Plaquetec Ltd. and a lab at the Babraham Institute has demonstrated the druggability of a pro-inflammatory protein discovered by Plaquetec.
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Citing Supreme Court, Second Circuit rules against FTC position

May 14, 2024
By Mari Serebrov
Buyers challenging patent settlements involving Forest Laboratories LLC’s blood pressure drug, Bystolic (nebivolol), failed to show the deals were illegal pay-for-delay arrangements, the U.S. Court of Appeals for the Second Circuit said in unanimously affirming a lower court’s two-time dismissal of the buyers’ antitrust suit.
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Pill in immersive interface

Bio Korea 2024: AI teeters toward ‘necessity’ in new drug R&D

May 14, 2024
By Marian (YoonJee) Chu
As the average cost of new drug R&D continues to skyrocket, the perception around using artificial intelligence (AI) as a tool to boost drug discovery is changing. “Developing new AI-based drugs is a difficult task, not only for Korea but also for countries with leading AI technology,” Hyeyun Jung, principal researcher of Korea Health Industry Development Institute’s Center for Health Industry Policy, told the audience at the Bio Korea meeting on May 9. “But there is a change in perception; [namely that] applying AI to new drug development is not an option but a necessity.”
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Elixir-Medical----DynamX-expanded-in-vessel.jpg
EuroPCR 2024

Elixir’s Dynamx bioadaptor superior to Medtronic Resolute Onyx DES

May 14, 2024
By Shani Alexander
Two-year data from Elixir Medical Corp.’s Bioadaptor randomized controlled trial showed that there is a significant clinical advantage in using its Dynamx coronary drug-eluting bioadaptor system over Medtronic plc’s Resolute Onyx drug-eluting stent in patients with coronary artery disease.
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Illustration of abdominal aortic aneurysm
EuroPCR 2024

PCI better for aortic stenosis, coronary disease than surgery

May 14, 2024
By Shani Alexander
Data from the transcatheter valve and vessel trial showed that percutaneous interventions in patients with aortic stenosis and coronary disease resulted in significantly lower mortality rates than those receiving surgical treatment.
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Endologix DETOUR

DETOUR2 shows Endologix superficial femoral artery bypass on track

May 13, 2024
By Annette Boyle
One-year results of the DETOUR2 trial published in the Journal of Vascular Surgery demonstrate outstanding results for Endologix LLC’s percutaneous transmural arterial bypass system for treatment of severe peripheral artery disease. The study showed nearly all patients experienced improvement in acute limb ischemia with freedom from occlusion of 92% and freedom from revascularization of nearly 88% at 12 months.
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CRISPR Cas9 illustration
Cardiovascular

Crispr Therapeutics announces new programs targeting refractory hypertension and acute hepatic porphyria

May 10, 2024
Crispr Therapeutics AG has expanded its in vivo pipeline with two new programs, which utilize lipid nanoparticle (LNP)-based delivery of CRISPR/Cas9 gene-editing cargo to the liver.
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Pill in immersive interface

Bio Korea 2024: AI teeters toward ‘necessity’ in new drug R&D

May 9, 2024
By Marian (YoonJee) Chu
As the average cost of new drug R&D continues to skyrocket, the perception around using artificial intelligence (AI) as a tool to boost drug discovery is changing. “Developing new AI-based drugs is a difficult task, not only for Korea but also for countries with leading AI technology,” Hyeyun Jung, principal researcher of Korea Health Industry Development Institute’s Center for Health Industry Policy, told the audience at the Bio Korea meeting on May 9. “But there is a change in perception; [namely that] applying AI to new drug development is not an option but a necessity.”
Read More
FieldForce Catheter

Field Medical begins first-in-human trials for ventricular PFA

May 9, 2024
By Annette Boyle
Field Medical Inc. kicked off its first-in-human study for its Fieldforce ablation system, designed for use in ventricular arrhythmias. The Ventricular Catheter Ablation Study study will enroll 60 patients in five centers around the world, most recently kicking off in the Na Homolce Hospital in Prague, Czech Republic.
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