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BioWorld - Tuesday, April 7, 2026
Home » Topics » Disease categories and therapies » Cardiovascular

Cardiovascular
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Cardiovascular

Nextgen Bioscience presents new autotaxin inhibitors

Feb. 15, 2024
Nextgen Bioscience Co. Ltd. has divulged ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2; autotaxin) inhibitors reported to be useful for the treatment of cancer, fibrosis, cardiovascular, inflammatory, respiratory, metabolic, eye and renal disorders, among others.<
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Neurology/Psychiatric

New mouse model of COVID-19-induced cerebrovascular embolic complications

Feb. 15, 2024
Researchers from Mercer University have presented a middle cerebral artery/ferric chloride (MCA/FeCl3) thromboembolic mouse model of COVID-19-induced stroke and cerebrovascular complications.
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4-9-Abbott-Triclip.png

FDA advisory committee gives Abbott a valentine with Triclip endorsement

Feb. 14, 2024
By Annette Boyle
Just in time for Valentine’s Day, the circulatory system devices panel of the medical devices advisory committee for the U.S. FDA showed some love for Abbott Laboratories’ Triclip transcatheter edge-to edge repair (TEER) system for leaky tricuspid heart valves.
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Biomarkers

TLNRD1 identified as new regulator of CCM signaling

Feb. 13, 2024
Researchers from Broad Institute Inc. and affiliated organizations have reported data from a study that highlighted a new variant-to-gene-to-program (V2G2P) approach designed to link variants from genome-wide association studies (GWAS) to genes and identify their convergence onto specific disease-associated transcriptional programs.
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Woman in pain holding hand over heart

CSL’s phase III misses primary endpoint in reducing cardiac events

Feb. 12, 2024
By Tamra Sami
CSL Ltd. will review the data further to see if there is a path forward for CSL-112 (human apolipoprotein A-I) after the phase III AEGIS-II trial failed to meet the primary efficacy endpoint in reducing the risk of major adverse cardiovascular events in patients following an acute heart attack.
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Toku Clair platform

Toku receives CE, UKCA marks for cardio disease AI risk evaluation tool

Feb. 8, 2024
By Shani Alexander
Toku Inc. recently obtained CE and UKCA marks for its artificial intelligence (AI) technology, Clair, which evaluates the risk of cardiovascular disease (CVD) using retinal images captured during an eye exam.
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CPR AED device
Patents

CU Medical develops system combining CPR and AED

Feb. 6, 2024
By Simon Kerton
South Korea’s CU Medical Systems Inc. has applied for protection of a system that combines features of a cardiopulmonary resuscitation (CPR) device and an automatic external defibrillator (AED) and uses chest impedance measurements to optimize emergency treatment.
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3D illustration of heart cross section

Bridgebio seeks Japan approval of acoramidis for rare heart disease

Feb. 5, 2024
By Marian (YoonJee) Chu
Armed with strong phase III safety data in Japanese patients, Palo Alto, Calif.-based Bridgebio Pharma Inc. is planning to file for Japan approval of its investigational drug acoramidis for a rare heart disorder.
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3D illustration of heart cross section

Bridgebio seeks Japan approval of acoramidis for rare heart disease

Feb. 5, 2024
By Marian (YoonJee) Chu
Armed with strong phase III safety data in Japanese patients, Palo Alto, Calif.-based Bridgebio Pharma Inc. is planning to file for Japan approval of its investigational drug acoramidis for a rare heart disorder.
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MHRA logo

UK’s MHRA relaxes restrictions on use of paclitaxel devices in PAD

Feb. 5, 2024
The controversy over the use of paclitaxel (PTX) in devices used to treat peripheral artery disease (PAD) has taken roughly half a decade to unwind as regulatory agencies across the globe stand down their restrictions on the use of these devices.
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