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BioWorld - Sunday, April 5, 2026
Home » Topics » Disease categories and therapies » Gastrointestinal

Gastrointestinal
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Novo Nordisk to launch Wegovy in South Korea mid-October

Oct. 7, 2024
By Marian (YoonJee) Chu
Danish pharma giant Novo Nordisk A/S is set to launch its blockbuster glucagon-like peptide-1 therapy, Wegovy (semaglutide), in South Korea’s growing obesity therapeutics market next week, a company official confirmed to BioWorld.
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Dermatologic

Triveni supports pipeline expansion with series B financing

Oct. 3, 2024
Triveni Bio Inc. has announced a $115 million series B financing to support expansion of its pipeline.
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Intestine
Gastrointestinal

Shattuck Labs to focus on DR3 antagonist antibody for IBD

Oct. 2, 2024
Shattuck Labs Inc. has announced a strategic shift to focus on SL-325, a death receptor 3 (DR3) antagonist antibody for the treatment of inflammatory bowel disease (IBD) and other inflammatory autoimmune diseases.
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Hands holding holographic intestine

On the magrolimab slab: Shattuck chalks latest CD47 bust in AML

Oct. 1, 2024
By Randy Osborne
Shattuck Labs Inc. opted, as one analyst put the matter, to do “the right thing early” by ending the clinical program with phase I-stage SL-172154 and shift resources to SL-325, a death receptor 3 antagonist, initially for inflammatory bowel disease, where TL1A/DR3-blocking antibodies have shown compelling monotherapy efficacy.
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predict hepatic encephalopathy
Patents

Machine learning tool predicts hepatic encephalopathy

Sep. 27, 2024
By Simon Kerton
A collaborating team of researchers from the U.K.’s University College London and the Incliva Biomedical Research Institute in Valencia, Spain, filed for protection of a machine learning model called AMMON-OHE to predict occurrence of overt hepatic encephalopathy in patients with cirrhosis of the liver.
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Gastrointestinal system with ulcerative colitis.
Gastrointestinal

Palisade submits CTA for PDE4 inhibitor prodrug for ulcerative colitis

Sep. 26, 2024
Palisade Bio Inc. has submitted a clinical trial application (CTA) for PALI-2108 for the treatment of ulcerative colitis, following a pre-CTA consultation meeting with Health Canada. Pending clearance, the company anticipates initiating a phase I study by year-end.
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Global currency
Neurology/psychiatric

Grants support Mabylon’s programs for ALS and inflammatory bowel disease

Sep. 25, 2024
Mabylon AG has been awarded three grants totaling more than CHF1.3 million (US$1.5 million) from Innosuisse Swiss Innovation Agency, Target ALS and the ALS Association.
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Astellas patent survives ‘natural law’ decision

Sep. 24, 2024
By Mari Serebrov
The U.S. Court of Appeals for the Federal Circuit reined in a district court that invalidated three claims in an Astellas Pharma Inc. patent protecting bladder drug Myrbetriq (mirabegron) based on a issue that was never argued.
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Gastrointestinal

New CXXC5/DVL interaction inhibitors disclosed in CK Regeon patent

Sep. 20, 2024
CK Regeon Inc. has divulged indirubin derivatives acting as CXXC-type zinc finger protein 5 (CXXC5)/DVL interaction inhibitors reported to be useful for the treatment of skin lesions, wounds, neurodegeneration, metabolic disorders and bone disorders.
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Astellas patent survives ‘natural law’ decision

Sep. 19, 2024
By Mari Serebrov
The U.S. Court of Appeals for the Federal Circuit reined in a district court that invalidated three claims in an Astellas Pharma Inc. patent protecting bladder drug Myrbetriq (mirabegron) based on a issue that was never argued.
Read More
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