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BioWorld - Tuesday, February 10, 2026
Home » Topics » Disease categories and therapies » Hematologic

Hematologic
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Novel hemophilia A murine model to test IdeS proteinase efficacy

July 18, 2022

CM-352 reduces MMP10-driven fibrinolysis in rivaroxaban-associated ICH

July 15, 2022

FVIII-QQ gene transfer therapy shows advantage for treating hemophilia A

July 14, 2022
Sickle cell disease

Limitations of certain mouse models for sickle cell research highlighted

July 8, 2022
By Helen Albert
Research carried out by a team at St. Jude Children's Research Hospital in Memphis highlights the importance of carefully assessing the mouse model you plan to use before starting preclinical medical research.
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Limitations of certain mouse models for sickle cell research highlighted

July 8, 2022

New coagulation factor XIa inhibitors discovered at Shanghai Leadingtac Pharmaceutical

July 7, 2022

KalVista Pharmaceuticals patents FXIIa inhibitors

June 29, 2022
Sickle cells

Precision, Novartis ink $1.4B in vivo gene editing deal for sickle cell disease

June 22, 2022
By Jennifer Boggs
As fellow gene editing firm Crispr Therapeutics AG hosted an innovation day in which it confirmed plans for regulatory filings by year-end for an ex vivo gene editing therapy in sickle cell disease and beta-thalassemia, Precision Biosciences Inc. announced plans to develop an in vivo gene editing approach through a collaboration with Novartis AG that brings Precision an initial $75 million with up to $1.4 billion in potential milestones.
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Merck & Co. identifies new FXIa and/or KLKB1 inhibitors

June 16, 2022

Conference data for June 14, 2022: EHA

June 14, 2022
New and updated preclinical and clinical data presented by biopharma firms at the European Hematology Association Congress, including: Abbvie, Affimed, Agios, Ascentage, Canbridge, Crispr, Daiichi, Disc, Genmab, Iaso, Innovent, Mustang, Novartis, Vertex, XNK.
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