Abera Bioscience AB has announced, together with clinical partner Radboud University Medical Center, the submission of a clinical trial application in the Netherlands to initiate a phase I trial of its serotype-independent pneumococcal vaccine candidate AB-01.12.
Outer membrane vesicles (OMVs), naturally released by gram-negative bacteria, are promising platforms for mucosal vaccines due to their immunostimulatory properties and ability to display antigens. Abera Bioscience AB previously developed an OMV platform using genetically engineered bacteria with covalent antigen decoration via Spycatcher/Tag technology.
The HIV vaccine field is increasingly focusing on inducing broadly neutralizing antibodies (bNAbs) that can recognize the virus’s genetic diversity. Recent experimental approaches include germline-targeting vaccines, sequential immunization strategies, mRNA-based immunogens, and nanoparticle platforms displaying engineered HIV envelope (Env) trimers. Several studies published in 2025 and 2026 how these designs guide antibody maturation in humans and generate broad neutralizing responses in nonhuman primates, although no HIV vaccine has yet demonstrated protective efficacy in large clinical trials.
Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. has patented integrin α4β7 (LPAM-1) antagonists that are potentially useful for the treatment of autoimmune disease, ulcerative colitis and Crohn’s disease.
Another day, another two multibillion-dollar deals with Asian companies, this time involving Dizal Pharmaceutical Co. Ltd. and its EGFR inhibitor for lung cancer, as well as Innovent Biologics Inc. and its anti-CD40L antibody for a chronic fibroinflammatory condition.
Hansoh Pharmaceutical Group Co. Ltd. has taken a new step in the evolution of China’s “newco” strategy, combining its newly created U.S. company, Avere Therapeutics Inc., with Nasdaq-listed Nextcure Inc. in a deal designed less to merge pipelines than to create a public vehicle for global development of a China-originated asset.
Signs of recovery are emerging in the biotechnology investment sector, although investors across Asia say that capital is flowing selectively to companies that can demonstrate clinical differentiation, strong management teams and a clear path to commercialization.
The field of cell and gene therapy is moving toward a new phase of scalability and clinical durability, with in vivo chimeric antigen receptor (CAR) T-cell therapeutics emerging as the dark horse in what speakers at BIO Asia-Taiwan 2026 described as CAR T’s second revolution.
The field of cell and gene therapy is moving toward a new phase of scalability and clinical durability, with in vivo chimeric antigen receptor (CAR) T-cell therapeutics emerging as the dark horse in what speakers at BIO Asia-Taiwan 2026 described as CAR T’s second revolution.
Hinova Pharmaceuticals Inc. has patented new molecular glue degraders comprising E3 ubiquitin-protein ligase binding agents acting as proto-oncogene Vav (VAV1) degradation inducers. As such, they are reported to be potentially useful for the treatment of autoimmune diseases, inflammatory disorders and cancer.
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