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BioWorld - Monday, December 22, 2025
Home » Topics » Disease categories and therapies » Immune

Immune
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3D molecular view of liquid-liquid phase separation
Immune

Condensates and innate immunity in Clarivate’s Citation Laureates

Sep. 30, 2025
By Mar de Miguel
No Comments
Clarivate plc has unveiled the 2025 Citation Laureates. Widely considered a predictor of the Nobel Prizes, this recognition has highlighted the discovery of biomolecular condensates in chemistry and the innate immunity signaling pathway in physiology or medicine, as well as the identification of leukemia stem cells and ghrelin, the so-called hunger hormone.
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 29, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, in Barcelona, which ended Sept. 26, addressed this question
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Cellular senescence may trigger MS progression

Sep. 26, 2025
By Xavier Bofill Bruna
No Comments
Is there a link between cellular senescence and multiple sclerosis (MS) progression? Several presentations at this year’s European Committee for Treatment and Research in Multiple Sclerosis 2025 (ECTRIMS 2025) conference, which ends today in Barcelona, addressed this question.
Read More
Illustration of antibodies attacking nerve cells
Immune

Aera Therapeutics selects AERA-109 for autoimmune diseases

Sep. 25, 2025
No Comments
Aera Therapeutics Inc. has nominated AERA-109, a targeted in vivo CAR T therapy designed to treat multiple B cell-mediated autoimmune diseases, as the company’s first development candidate. AERA-109 leverages Aera’s proprietary targeted lipid nanoparticle (tLNP) delivery platform and CAR T technology.
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3D molecular view of liquid-liquid phase separation
Immune

Condensates and innate immunity in Clarivate’s Citation Laureates

Sep. 25, 2025
By Mar de Miguel
No Comments
Clarivate plc has unveiled the 2025 Citation Laureates. Widely considered a predictor of the Nobel Prizes, this recognition has highlighted the discovery of biomolecular condensates in chemistry and the innate immunity signaling pathway in physiology or medicine, as well as the identification of leukemia stem cells and ghrelin, the so-called hunger hormone.
Read More
IPO, coins, financial chart

Genfleet raises $234M with Hong Kong IPO

Sep. 23, 2025
By Marian (YoonJee) Chu
No Comments
Genfleet Therapeutics (Shanghai) Inc. debuted on the Hong Kong Stock Exchange on its second attempt at an IPO, raising HK$1.819 billion (US$234 million). Genfleet’s shares (HKEX:2595) rose to HK$44.00 at the opening bell on Sept. 19 and closed at HK$42.10, about 106% higher than the listing price.
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Gloved hands holding mRNA vaccine vial
Immune

GC Biopharma files Korean IND for COVID-19 mRNA vaccine

Sep. 23, 2025
No Comments
GC Biopharma Corp. has filed an IND application with the South Korean Ministry of Food and Drug Safety (MFDS) for a phase I trial of GC-4006A, an mRNA vaccine candidate for COVID-19.
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Immune

Leads Biolabs’ LBL-047 gains IND approval for autoimmune diseases

Sep. 22, 2025
No Comments
Nanjing Leads Biolabs Co. Ltd. has received IND approval from the FDA for LBL-047, its first autoimmune therapeutic candidate to enter the clinic.
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Test tube, dropper
Immune

IND clearance for HDT Bio’s HDT-321 for Crimean-Congo hemorrhagic fever

Sep. 22, 2025
No Comments
The FDA has cleared HDT Bio Corp.’s IND application for HDT-321, a first-in-class prophylactic designed to protect against Crimean-Congo hemorrhagic fever (CCHF).
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IPO, coins, financial chart

Genfleet raises $234M with Hong Kong IPO

Sep. 19, 2025
By Marian (YoonJee) Chu
No Comments
Genfleet Therapeutics (Shanghai) Inc. debuted on the Hong Kong Stock Exchange on its second attempt at an IPO, raising HK$1.819 billion (US$234 million). Genfleet’s shares (HKEX:2595) rose to HK$44.00 at the opening bell on Sept. 19 and closed at HK$42.10, about 106% higher than the listing price.
Read More
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