Aurinia Pharmaceuticals Inc. is suspending further development of voclosporin ophthalmic solution (VOS) for dry eye syndrome after a dose-ranging trial of the candidate failed to meet its primary endpoint of improving a measure of the condition after four weeks of treatment.
A multi-institutional team of researchers has implicated lipid droplets, which are key energy storage units of individual cells, in innate immune defense. "Until now it was thought that [lipid droplets] were at the service of viruses or bacteria during infection," Albert Pol told BioWorld. The new study, which was published in the Oct. 16, 2020, issue of Science, demonstrated that cells also use the droplets to coordinate their defense.
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