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BioWorld - Sunday, January 25, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Pill in immersive interface
Immune

Deepcure selects DC-9476 for autoimmune diseases

Aug. 13, 2024
Deepcure Inc. has selected its first artificial intelligence (AI)-generated candidate, DC-9476, for autoimmune disease.
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Concept of business partnership

Genor wins $440M+ cancer drug deal with Third Rock/Two River firm

Aug. 13, 2024
By Marian (YoonJee) Chu
China’s Genor Biopharma Co. Ltd. agreed to out-license GB-261, its bispecific antibody candidate primarily targeting B-cell lymphomas, to TRC 2004 Inc., a U.S.-based newco co-founded by Third Rock Ventures LLC and Two River Group Holdings LLC.
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ARS wins FDA nod for needle-free Neffy in allergic reactions

Aug. 12, 2024
By Jennifer Boggs
Executives of ARS Pharmaceuticals Inc. are anticipating a quick switch for severe allergy patients following the U.S. FDA approval of Neffy (epinephrine nasal spray 2 mg), marking the first needle-free treatment option.
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Cullinan ends $625M deal, returns Harbour’s cancer drug

Aug. 12, 2024
By Marian (YoonJee) Chu
Cullinan Therapeutics Inc. terminated development of Harbour Biomed Holdings Ltd.’s bispecific B7H4 x 4-1BB immune activator, CLN-418 (HBM-7008), after reviewing phase I data.
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Immune

Epics Therapeutics patents METTL3 inhibitors

Aug. 12, 2024
Epics Therapeutics SA has described N6-adenosine-methyltransferase catalytic subunit (METTL3) inhibitors reported to be useful for the treatment of autoimmune disease, cancer, infections, and neurological and inflammatory disorders.
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Multiple sclerosis-damaged myelin
Neurology/psychiatric

Azer-cel gets IND clearance in multiple sclerosis

Aug. 12, 2024
Precision Biosciences Inc. has announced that its experimental allogeneic T cell therapy azercabtagene zapreleucel (azer-cel) for the treatment of multiple sclerosis (MS) has received IND clearance from the FDA.
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3D rendering of CAR T therapy in cell
Immune

BCMA-targeting CAR T cell cleared for clinic by China’s NMPA

Aug. 12, 2024
CSPC Pharmaceutical Group Ltd. has received clearance from China’s National Medical Products Administration (NMPA) to conduct clinical trials in China with its BCMA-targeting CAR T cell SYS-6020 for systemic lupus erythematosus (lupus) in China.
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Concept of business partnership

Genor wins $440M+ cancer drug deal with Third Rock/Two River firm

Aug. 7, 2024
By Marian (YoonJee) Chu
China’s Genor Biopharma Co. Ltd. agreed to out-license GB-261, its bispecific antibody candidate primarily targeting B-cell lymphomas, to TRC 2004 Inc., a U.S.-based newco co-founded by Third Rock Ventures LLC and Two River Group Holdings LLC.
Read More
Handshake with DNA, molecules

Otsuka to buy Boston chemoproteomics biotech for up to $1.1B

Aug. 6, 2024
By Marian (YoonJee) Chu
Tokyo-headquartered Otsuka Pharmaceutical Co. Ltd. said Aug. 1 that it will acquire Boston-based Jnana Therapeutics Inc. through a potential $1.125 billion M&A deal. Under the terms, Otsuka will work to close the transaction by the third quarter of 2024, with $800 million paid out to Jnana shareholders, along with up to $325 million in additional development and regulatory milestones payments.
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Handshake with DNA, molecules

Otsuka to buy Boston chemoproteomics biotech for up to $1.1B

Aug. 2, 2024
By Marian (YoonJee) Chu
Tokyo-headquartered Otsuka Pharmaceutical Co. Ltd. said Aug. 1 that it will acquire Boston-based Jnana Therapeutics Inc. through a potential $1.125 billion M&A deal. Under the terms, Otsuka will work to close the transaction by the third quarter of 2024, with $800 million paid out to Jnana shareholders, along with up to $325 million in additional development and regulatory milestones payments.
Read More
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