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BioWorld - Sunday, April 19, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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Immune

Rubedo Life Sciences patents new Bcl-xl inhibitors

June 25, 2025
Work at Rubedo Life Sciences Inc. has led to the development of Bcl-2-like protein 1 (Bcl-xl; Bcl-X; BCL2L1) inhibitors acting as senolytic agents and reported to be useful for the treatment of autoimmune disease, cancer, cardiovascular disorders, cognitive disorders, diabetes, inflammatory, metabolic and neurological disorders, among others.
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T cells
Immune

Cue Biopharma holds pre-IND meeting with FDA for lead autoimmune asset

June 25, 2025
No Comments
Cue Biopharma Inc. has received pre-IND feedback from the FDA to discuss the proposed development plan for CUE-401, its lead autoimmune asset. Based on FDA feedback, the company intends to file an IND pending completion of final IND-enabling studies.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow

Otsuka licenses Harbour’s bispecific T-cell engager for $670M

June 24, 2025
By Tamra Sami
No Comments
Harbour Biomed is out-licensing its B-cell maturation antigen and CD3 bispecific T-cell engager HBM-7020 for autoimmune diseases to Otsuka Pharmaceutical Co. Ltd. in a deal worth up to $670 million.
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Hand holding IPO, financial icons

Transthera raises $25M with Hong Kong IPO; stock up 78% on debut

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Transthera Sciences Inc. debuted on the Hong Kong stock exchange June 23 with a HK$200.95 million (US$25.6 million) IPO, becoming the latest in a string of mainland Chinese biopharmaceutical firms to turn to the Hong Kong market for capital.
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Drug Farm harvests new immunomodulators with AI-gene editing tech

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Yao Yuan Biotechnology Ltd., also known as Drug Farm, is advancing a portfolio of immune-modulating therapies for various indications including hepatitis B virus, hepatocellular cancer and a relatively new rare genetic disease called ROSAH, an acronym for retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache.
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3D rendering of CAR T therapy in cell
EAN 2025

CAR T cells take on neurological disorders, though sometimes still one patient at a time

June 24, 2025
By Anette Breindl
No Comments
At the 11th Congress European Academy of Neurology, which was held in Helsinki June 21 to June 24, researchers presented new data on using CAR T cells in autoimmune neurological conditions.
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Hand holding IPO, financial icons

Transthera raises $25M with Hong Kong IPO; stock up 78% on debut

June 23, 2025
By Marian (YoonJee) Chu
No Comments
Transthera Sciences Inc. debuted on the Hong Kong stock exchange June 23 with a HK$200.95 million (US$25.6 million) IPO, becoming the latest in a string of mainland Chinese biopharmaceutical firms to turn to the Hong Kong market for capital.
Read More
Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow

Otsuka licenses Harbour’s bispecific T-cell engager for $670M

June 23, 2025
By Tamra Sami
No Comments
Harbour Biomed is out-licensing its B-cell maturation antigen and CD3 bispecific T-cell engager HBM-7020 for autoimmune diseases to Otsuka Pharmaceutical Co. Ltd. in a deal worth up to $670 million.
Read More
Vaccine vials and syringe
Immune

CEPI-backed consortium to develop all-in-one filovirus vaccine

June 23, 2025
No Comments
A global consortium led by Adaptvac ApS aims to design and test a new vaccine that could offer broad protection against several filoviruses, including Zaire ebolavirus, Sudan ebolavirus and Marburg virus.
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immune

Otsuka licenses Harbour Biomed’s BCMAxCD3 bispecific T-cell engager HBM-7020

June 23, 2025
No Comments
Harbour Biomed Ltd. has established a global strategic collaboration with Otsuka Pharmaceutical Co. Ltd. to advance BCMAxCD3 bispecific T-cell engagers for the treatment of autoimmune diseases.
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