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BioWorld - Wednesday, July 29, 2026
Home » Topics » Disease categories and therapies » Immune

Immune
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HIV virus
HIV/AIDS

AIDS 2026: New targets for metabolic dysfunction despite ART

July 29, 2026
By Mar de Miguel
No Comments
Although antiretroviral therapy (ART) can suppress HIV to undetectable levels, a growing body of evidence suggests that the virus leaves a lasting biological imprint. At the 26th International AIDS Conference (AIDS 2026), researchers reported persistent abnormalities affecting the gut, cardiovascular system, metabolism and immune function despite effective viral control.
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Lee-Cheng Liu, chairman, Taiwan BIO
BIO Asia-Taiwan 2026

Taiwan biotech looks outward in next phase of growth

July 28, 2026
By Marian (YoonJee) Chu
No Comments
Taiwan’s biotechnology sector was built around domestic health needs, including vaccines and drug manufacturing, but it is increasingly looking outward – to international partnerships, licensing, clinical development and a bigger role in the global biomedical ecosystem.
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Illustration of dopamine signaling in the brain
Neurology/psychiatric

New schizophrenia targets challenge trial design

July 28, 2026
By Mar de Miguel
No Comments
The search for better schizophrenia therapies is moving beyond dopamine toward a growing number of experimental targets. According to researchers, the repeated failures of some late-stage programs may reflect not only the complexity of the disease, but also the need to better identify the patients most likely to benefit from each approach.
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Lee-Cheng Liu, chairman, Taiwan BIO
BIO Asia-Taiwan 2026

Taiwan biotech looks outward in next phase of growth

July 27, 2026
By Marian (YoonJee) Chu
No Comments
Taiwan’s biotechnology sector was built around domestic health needs, including vaccines and drug manufacturing, but it is increasingly looking outward – to international partnerships, licensing, clinical development and a bigger role in the global biomedical ecosystem.
Read More
Antibodies artwork

Argenx expands immune pipeline in $2.2B cash acquisition of Forte

July 27, 2026
By Nuala Moran
No Comments
In a rare event for the European biotech sector, Dutch/Belgian immunology specialist Argenx SE is to acquire a U.S. counterpart, Forte Biosciences Inc., in an all cash deal valued at $2.2 billion. The price of $77 per share is a premium of about 86% to Forte’s volume-weighted average price since it reported positive phase Ib data for the lead program FB-102 in vitiligo on July 9.
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Immune

Innovstone Therapeutics discloses new cathepsin C inhibitors

July 27, 2026
Innovstone Therapeutics Ltd. has synthesized cathepsin C (dipeptidyl peptidase I; DPP-1) inhibitors found to be potentially useful for the treatment of autoimmune diseases and cancer.
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Streptococcus pneumoniae in lungs
Immune

Abera seeks clinical trial clearance for AB-01.12

July 23, 2026
No Comments

Abera Bioscience AB has announced, together with clinical partner Radboud University Medical Center, the submission of a clinical trial application in the Netherlands to initiate a phase I trial of its serotype-independent pneumococcal vaccine candidate AB-01.12.


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Influenza virus
Infection

Intranasal vaccine platform induces immunity against influenza

July 23, 2026
No Comments
Outer membrane vesicles (OMVs), naturally released by gram-negative bacteria, are promising platforms for mucosal vaccines due to their immunostimulatory properties and ability to display antigens. Abera Bioscience AB previously developed an OMV platform using genetically engineered bacteria with covalent antigen decoration via Spycatcher/Tag technology.
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HIV particles emerging from an infected T cell
HIV/AIDS

Developing an HIV vaccine, one small step at a time

July 23, 2026
By Mar de Miguel
No Comments
The HIV vaccine field is increasingly focusing on inducing broadly neutralizing antibodies (bNAbs) that can recognize the virus’s genetic diversity. Recent experimental approaches include germline-targeting vaccines, sequential immunization strategies, mRNA-based immunogens, and nanoparticle platforms displaying engineered HIV envelope (Env) trimers. Several studies published in 2025 and 2026 how these designs guide antibody maturation in humans and generate broad neutralizing responses in nonhuman primates, although no HIV vaccine has yet demonstrated protective efficacy in large clinical trials.
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Immune

Hubei Bio-Pharmaceutical Industrial Technological Institute discloses new LPAM-1 antagonists

July 22, 2026
Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. has patented integrin α4β7 (LPAM-1) antagonists that are potentially useful for the treatment of autoimmune disease, ulcerative colitis and Crohn’s disease.
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