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Home » Topics » Disease categories and therapies » Infection

Infection
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Chinese flag and pills

China clears more first-in-class innovative drugs than ever before

April 7, 2025
By Tamra Sami
China approved 48 first-in-class innovative drugs, as well as a significant number of medications for pediatric and rare diseases, thanks to measures aimed at enhancing review efficiency and accelerating patient access to novel therapies, according to a report released by China’s National Medical Products Administration.
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Infection

NSTDA discovers new viral replication inhibitors

April 7, 2025
National Science & Technology Development Agency (NSTDA) has described cordycepin derivatives acting as viral replication inhibitors reported to be useful for the treatment of viral infections.
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Researcher in lab with Petri dishes.
Infection

Blacksmith presents FG-2101 for gram-negative bacterial infections

April 7, 2025
Using its proprietary FBDD platform, Blacksmith discovered FG-2101, the prodrug form of FG-960, the first known non-hydroxamate LpxC inhibitor that exerted activity against LpxC at the nanomolar range.
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DNA testing illustration

With ‘wholesale assault’ on research, bipartisan alarm at institutional failure

April 4, 2025
By Anette Breindl
Biomedical research seems like it should be the ultimate bipartisan issue. But under the Trump administration, unless and until Congress regains its will to make use of its constitutional powers, bipartisan support for research seems to be a thing of the past.
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Infection

Amenis Bioscience describes new PIN1 and viral replication inhibitors

April 4, 2025
Amenis Bioscience Inc. has identified anthranilic acid derivatives acting as peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) and viral replication inhibitors reported to be useful for the treatment of parasitic and viral infections, obesity, cancer, nonalcoholic or metabolic dysfunction-associated steatohepatitis (NASH/MASH), inflammatory bowel disease and pulmonary fibrosis.
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Infection

Polymyxin analogues for gram-negative bacterial infections disclosed in Wellpep patent

April 4, 2025
Wellpep Co. Ltd. has divulged polymyxin analogues reported to be useful for the treatment of gram-negative bacterial infections.
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DNA testing illustration
Policy

With ‘wholesale assault’ on research, bipartisan alarm at institutional failure

April 4, 2025
By Anette Breindl
Biomedical research seems like it should be the ultimate bipartisan issue. But under the Trump administration, unless and until Congress regains its will to make use of its constitutional powers, bipartisan support for research seems to be a thing of the past. On March 3, members of the National Academies of Science, Engineering and Medicine warned that the second Trump administration has been waging a “wholesale assault” on American research.
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Enterobacteriaceae
Infection

Arrepath’s antibiotic targeting Enterobacterales receives CARB-X funding

April 4, 2025
Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award Arrepath Inc. $3.7 million to execute a lead optimization workplan for its first-in-class antibiotic targeting a clinically novel target for the treatment of complicated urinary tract infections caused by multidrug-resistant Enterobacterales.
Read More
DNA testing illustration

With ‘wholesale assault’ on research, bipartisan alarm at institutional failure

April 3, 2025
By Anette Breindl
Biomedical research seems like it should be the ultimate bipartisan issue. But under the Trump administration, unless and until Congress regains its will to make use of its constitutional powers, bipartisan support for research seems to be a thing of the past. On March 3, members of the National Academies of Science, Engineering and Medicine warned that the second Trump administration has been waging a “wholesale assault” on American research.
Read More
SARS-CoV-2 illustration turns from blue to red
Infection

Shionogi’s S-880008 shows broad range of activity against SARS-CoV-2 variants

April 3, 2025
COVID-19 has continued to alarm public health, and although several therapeutics and vaccines have been developed, the development of effective vaccines or antibodies is challenging due to mutations in the surface of the spike protein in the SARS-CoV-2 virus.
Read More
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