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Home » Topics » Disease categories and therapies » Infection

Infection
Infection RSS Feed RSS

Spero with white knight GSK succeed with UTI treatment

May 28, 2025
By Lee Landenberger
No Comments
GSK plc knew a good thing when it swooped in nearly three years ago to rescue Spero Therapeutics Inc.’s oral antibiotic from a complete response letter (CRL). New pivotal phase III study data showed tebipenem pivoxil hydrobromide (HBr) for complicated urinary tract infections (cUTI), including pyelonephritis, hit its primary endpoint.
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AI-generated art for viral infection of the lungs
Infection

Apollo Therapeutics’ APL-10456 exerts strong immune response against rhinovirus

May 28, 2025
No Comments
Rhinovirus (RV) infection is among the most common respiratory infections causing exacerbations of chronic obstructive pulmonary disease and asthma. The high antigenic diversity of RV is a barrier to the development of effective cross-protective vaccines for RV infection.
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Gene editing illustration
Infection

New CRISPR-based antiviral strategy targets neurotrophic JC polyomavirus in 2D and 3D cell models

May 26, 2025
No Comments
Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system caused by lytic infection of oligodendrocytes by pathogenic strains of the JC polyomavirus (JCV). This opportunistic virus has long persisted as a serious threat during periods of immunosuppression, and currently, there is no effective antiviral treatment available.
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Chikungunya-virus
Index insights

Chikungunya wins boost Valneva; overall infectious disease stocks fall

May 22, 2025
By Amanda Lanier
No Comments
Infectious disease stocks stumbled in the early months of 2025, with the BioWorld Infectious Disease Index (BIDI) plunging 17.83% by the end of April, well behind the broader markets. By comparison, the Nasdaq Biotechnology Index slipped just 1.16%, and the Dow Jones Industrial Average declined 4.41%. In 2024, the BIDI ended the year down 6.28%, after hitting a low of -25.12% in late April.
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Infection

CSIC divulges new antiviral compounds for coronavirus acute respiratory syndrome

May 21, 2025
Consejo Superior de Investigaciones Científicas (CSIC) has synthesized antiviral compounds reported to be useful for the treatment of coronavirus acute respiratory syndrome.
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Phase HPV urine test

Phase Scientific raises $34M series A to advance urine-based diagnostics

May 20, 2025
By Tamra Sami
Phase Scientific International Ltd. raised $34 million in a series A round to accelerate research and development of its early disease detection technology for multiple cancers, women's health issues, and infectious diseases.
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US FDA rethinks COVID-19 boosters

May 20, 2025
By Mari Serebrov
No Comments
Five years after the COVID-19 pandemic gripped the world, the U.S. FDA is moving away from annual routine boosters for all children and adults. Instead of that one-size-fits-all regulatory framework by which it has granted broad COVID-19 vaccine marketing authorization for all Americans older than 6 months, the agency said it’s adopting a policy akin to that followed in Europe, which now restricts the vaccines to older adults and those at high risk for severe disease.
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Elderly person receiving shot

With FDA vaccine nod, Novavax takes ACIP of new COVID-19 rules

May 19, 2025
By Randy Osborne
No Comments
Frets about how the new federal administration might affect prospects for vaccines were quelled at least somewhat by the U.S. FDA green light for Novavax Inc.’s COVID-19 vaccine Nuvaxovid, indicated for adults 65 and over and people 12-64 years old with at least one underlying condition that puts them at risk of severe outcomes from infection by the virus.
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Zip p2 platform

Zip Diagnostics develops first rapid POC test for scabies

May 16, 2025
By Tamra Sami
Zip Diagnostics Pty Ltd., Menzies School of Health Research and Axxin Pty Ltd., a Melbourne, Australia-based diagnostic instrumentation manufacturer, partnered to develop a rapid diagnostic test for scabies, a skin parasite that affects more than 200 million people each year.
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urine testing device
Patents

Urine-testing device turns toilets into health trackers

May 16, 2025
By Simon Kerton
In what represents just the company’s third PCT filing, Houston-based Starling Medical Inc.’s co-founders, Hannah McKenney and William Hendricks, seek to gain further protection for their at-home urine diagnostic patient-monitoring platform that eliminates the traditional use of catching containers and dipsticks.
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