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Home » Topics » Disease categories and therapies » Infection

Infection
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Deal handshake with coin, chart background

Shionogi to acquire Japan Tobacco pharma companies for $1.1B

May 8, 2025
By Tamra Sami
No Comments
Shionogi & Co. said it plans to acquire Japan Tobacco Inc. (JT) subsidiaries Torii Pharmaceutical Co. and Akros Pharma Inc. for ¥160 billion (US$1.1 billion) to expand its global R&D business. The two companies have been negotiating since early 2024, and the deal is structured such that a tender offer will begin on May 8 and end on June 18 with an offer price of ¥6,350 per share to buy at least 11.89% of the minority stake, JT told BioWorld.
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Illustration of blood cells, Plasmodium causing malaria illness
Infection

Two cores better than one: combining carboline and triazole into small molecules against malaria

May 8, 2025
No Comments
Malaria continues to exact heavy financial and socioeconomic burdens in several parts of the world, with 249 million cases and more than 630,000 deaths reported in 2022. Two-thirds of malaria-related deaths occur among children younger than 5 years.
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HIV/AIDS

New HIV integrase inhibitors disclosed in Gilead patent

May 7, 2025
Gilead Sciences Inc. has divulged bridged tricyclic carbamoylpyridone prodrugs acting as HIV integrase inhibitors reported to be useful for the treatment of HIV infection.
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Tiger mosquito
Immune

Immunogenicity and efficacy of a bivalent self-amplifying RNA vaccine against yellow fever and Zika

May 7, 2025
No Comments
Researchers from the Access to Advanced Health Institute and collaborating institutions have developed a promising new bivalent vaccine candidate that can protect against both yellow fever and Zika viruses. The study demonstrates that the vaccine elicits robust humoral and cellular immune responses in mice and hamsters and provides complete protection against lethal viral challenges.
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Blood cells and bacteria

Deepull raises €50M for bloodstream infection test

May 1, 2025
By Shani Alexander
Deepull Diagnostics SL raised €50 million (US$56.93 million) in an oversubscribed series C financing round to complete clinical validation studies of its UllCORE diagnostic system for direct-from-blood rapid pathogen detection.
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US HHS touts NIH-developed universal vaccine platform

May 1, 2025
By Mari Serebrov
In a paradigm shift from private-sector partners, the U.S. Department of Health and Human Services (HHS) and the NIH announced May 1 the development of Generation Gold Standard, a next-generation, universal vaccine platform that uses a beta-propiolactone-inactivated, whole-virus to target pandemic-prone viruses.
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Illustrated diagram showing the various receptors of a natural killer cell
HIV/AIDS

Key genes and educated natural killer cells keep HIV in remission

April 30, 2025
By Mar de Miguel
Scientists at Institut Pasteur have gained new insights into how some people control HIV-1 replication after interruption of antiretroviral treatment (ART). The investigators found a fingerprint involved in long-term viral remission.
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Infection

Nuvobio divulges new peptides to treat C. neoformans infection

April 29, 2025
Nuvobio Corp. has synthesized peptides reported to be useful for the treatment of Cryptococcus neoformans infection.
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Infection

Ciprofloxacin prodrug effectively disrupts biofilm formation

April 29, 2025
Researchers from Foshan University described a ciprofloxacin prodrug designed to treat biofilm-associated drug-resistant P. aeruginosa infections.
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Drug vials and syringe

Vaccine Integrity Project launched to tackle ‘unfortunate reality’

April 25, 2025
By Nuala Moran
Nervousness about the Trump administration’s attitude to vaccines has spurred the formation of the Vaccine Integrity Project, which has the aim of safeguarding the use of vaccines and ensuring vaccine policy “remains grounded in the best available science,” and is “free from external influence.”
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