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Home » Topics » Disease categories and therapies » Infection

Infection
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Viruses

Pandemic potential is plentiful, but the next bug’s specifics are known unknown

April 9, 2025
By Anette Breindl
Compared to other forms of prevention, a unique issue for pandemic preparedness is that it is forever unclear what pathogen, exactly, the world needs to be prepared for. There are an estimated 300,000 viruses that infect mammals; add in birds, and the estimate grows to more than half a million. Some of those viruses are much greater threats than others.
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Red blood cells on blue background
Hematologic

Bayer’s BAY-3389934 allows optimal controllability in sepsis-induced coagulopathy treatment

April 9, 2025
Sepsis-induced coagulopathy (SIC) is a complication of sepsis tied to high mortality in patients. Anticoagulation using a coagulation factor IIa and Xa dual inhibitor might have the potential to improve the treatment of this severe condition.
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Chinese flag and pills

China clears more first-in-class innovative drugs than ever before

April 8, 2025
By Tamra Sami
China approved 48 first-in-class innovative drugs, as well as a significant number of medications for pediatric and rare diseases, thanks to measures aimed at enhancing review efficiency and accelerating patient access to novel therapies, according to a report released by China’s National Medical Products Administration.
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Syringe on map of Africa

Experts cite deadly consequences of PEPFAR funding disruption

April 8, 2025
By Nuala Moran
The extent of the damage that will be caused if the U.S. overseas aid program, the President’s Emergency Plan for AIDS Relief (PEPFAR), is axed or has its funding cut, is laid out in an expert analysis published in The Lancet April 8, which estimates nearly 500,000 children could die from AIDS-related causes by 2030, while 1 million children will be infected with the virus.
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Infection

Gilead Sciences describes new nucleoside prodrugs for viral infections

April 8, 2025
Gilead Sciences Inc. has identified nucleoside prodrugs reported to be useful for the treatment of viral infections.
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Mycobacterium tuberculosis
Infection

L3T mRNA vaccine platform shows preclinical prophylactic and therapeutic activity against TB

April 8, 2025
New vaccines to control tuberculosis (TB) are urgently needed to fight the global burden of the disease, the increase of resistant strains and the lack of effective vaccines to prevent latent TB infections.
Read More
Viruses
Infection

Pandemic potential is plentiful, but the next bug’s specifics are known unknown

April 8, 2025
By Anette Breindl
Compared to other forms of prevention, a unique issue for pandemic preparedness is that it is forever unclear what pathogen, exactly, the world needs to be prepared for. There are an estimated 300,000 viruses that infect mammals; add in birds, and the estimate grows to more than half a million. Some of those viruses are much greater threats than others.
Read More
Chinese flag and pills

China clears more first-in-class innovative drugs than ever before

April 7, 2025
By Tamra Sami
China approved 48 first-in-class innovative drugs, as well as a significant number of medications for pediatric and rare diseases, thanks to measures aimed at enhancing review efficiency and accelerating patient access to novel therapies, according to a report released by China’s National Medical Products Administration.
Read More
Infection

NSTDA discovers new viral replication inhibitors

April 7, 2025
National Science & Technology Development Agency (NSTDA) has described cordycepin derivatives acting as viral replication inhibitors reported to be useful for the treatment of viral infections.
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Researcher in lab with Petri dishes.
Infection

Blacksmith presents FG-2101 for gram-negative bacterial infections

April 7, 2025
Using its proprietary FBDD platform, Blacksmith discovered FG-2101, the prodrug form of FG-960, the first known non-hydroxamate LpxC inhibitor that exerted activity against LpxC at the nanomolar range.
Read More
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