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Home » Topics » Disease categories and therapies » Infection

Infection
Infection RSS Feed RSS

Deal handshake with coin, chart background

Shionogi to acquire Japan Tobacco pharma companies for $1.1B

May 13, 2025
By Tamra Sami
No Comments
Shionogi & Co. said it plans to acquire Japan Tobacco Inc. (JT) subsidiaries Torii Pharmaceutical Co. and Akros Pharma Inc. for ¥160 billion (US$1.1 billion) to expand its global R&D business. The two companies have been negotiating since early 2024, and the deal is structured such that a tender offer will begin on May 8 and end on June 18 with an offer price of ¥6,350 per share to buy at least 11.89% of the minority stake, JT told BioWorld.
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Illustration of measles virus particles
Infection

Invivyd initiates measles monoclonal antibody discovery program

May 13, 2025
No Comments
Invivyd Inc. has initiated a discovery program for a measles monoclonal antibody (mAb).
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Illustration of liver infection
Infection

ABI-4334 outperforms vebicorvir in HBV suppression

May 13, 2025
No Comments
Current therapies for chronic hepatitis B virus (HBV) infection can effectively suppress viral replication but do not achieve a functional or complete cure. Capsid assembly modulators inhibit the assembly of viral capsids, prevent the encapsidation of pregenomic RNA, and interfere with both the formation and amplification of covalently closed circular DNA, which is essential for viral persistence.
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Infection

US researchers patent new H+/K+-ATPase inhibitors

May 12, 2025
The Research Foundation of State University of New York and the U.S. Department of Health and Human Services have jointly developed prazole-based compounds acting as H+/K+-ATPase inhibitors and thus reported to be useful for the treatment of viral infections.
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Infection

Arrepath develops new LpxH (bacterial) inhibitors

May 12, 2025
Arrepath Inc. has patented new UDP-2,3-diacylglucosamine hydrolase (LpxH) (bacterial) inhibitors reported to be useful for the treatment of gram-negative bacterial infections.
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Deal handshake with coin, chart background

Shionogi to acquire Japan Tobacco pharma companies for $1.1B

May 8, 2025
By Tamra Sami
No Comments
Shionogi & Co. said it plans to acquire Japan Tobacco Inc. (JT) subsidiaries Torii Pharmaceutical Co. and Akros Pharma Inc. for ¥160 billion (US$1.1 billion) to expand its global R&D business. The two companies have been negotiating since early 2024, and the deal is structured such that a tender offer will begin on May 8 and end on June 18 with an offer price of ¥6,350 per share to buy at least 11.89% of the minority stake, JT told BioWorld.
Read More
Illustration of blood cells, Plasmodium causing malaria illness
Infection

Two cores better than one: combining carboline and triazole into small molecules against malaria

May 8, 2025
No Comments
Malaria continues to exact heavy financial and socioeconomic burdens in several parts of the world, with 249 million cases and more than 630,000 deaths reported in 2022. Two-thirds of malaria-related deaths occur among children younger than 5 years.
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HIV/AIDS

New HIV integrase inhibitors disclosed in Gilead patent

May 7, 2025
Gilead Sciences Inc. has divulged bridged tricyclic carbamoylpyridone prodrugs acting as HIV integrase inhibitors reported to be useful for the treatment of HIV infection.
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Tiger mosquito
Immune

Immunogenicity and efficacy of a bivalent self-amplifying RNA vaccine against yellow fever and Zika

May 7, 2025
No Comments
Researchers from the Access to Advanced Health Institute and collaborating institutions have developed a promising new bivalent vaccine candidate that can protect against both yellow fever and Zika viruses. The study demonstrates that the vaccine elicits robust humoral and cellular immune responses in mice and hamsters and provides complete protection against lethal viral challenges.
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Blood cells and bacteria

Deepull raises €50M for bloodstream infection test

May 1, 2025
By Shani Alexander
Deepull Diagnostics SL raised €50 million (US$56.93 million) in an oversubscribed series C financing round to complete clinical validation studies of its UllCORE diagnostic system for direct-from-blood rapid pathogen detection.
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