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Home » Topics » Disease categories and therapies » Infection

Infection
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Dollar sign in light bulb on yellow background

Report shows increased pharma innovation despite rising R&D costs

March 25, 2025
By Nuala Moran
The obesity market is driving pharma’s return on investment (ROI) upward, with the projected return rising to 5.9% overall in 2024, but only reaching 3.8% if GLP-1 assets are excluded. At the same time, the average cost of developing a drug continues to rise and now stands at $2.23 billion, compared to $2.12 billion in 2023, according to Deloitte’s 15th annual analysis of the ROI from pharmaceutical innovation.
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Closeup of Aedes mosquito on skin.
Infection

New symptomatic, immune-competent neonatal mouse model of dengue virus infection

March 25, 2025
Dengue virus (DENV) is a member of the flavivirus family causing dengue fever, a mosquito-borne disease that can be life-threatening. Despite DENV’s widespread presence in over 80 countries and the significant health burden posed by the infection, there is still a critical need for therapeutics and vaccines, with current treatment options only providing supportive care.
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CDC’s ACIP meeting rescheduled

March 24, 2025
By Karen Carey
A meeting of the CDC’s Advisory Committee on Immunization Practices (ACIP) was rescheduled for April 15-16, according to the Federal Register.
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Closeup of Aedes mosquito on skin.
Infection

New symptomatic, immune-competent neonatal mouse model of dengue virus infection

March 24, 2025
Dengue virus (DENV) is a member of the flavivirus family causing dengue fever, a mosquito-borne disease that can be life-threatening. Despite DENV’s widespread presence in over 80 countries and the significant health burden posed by the infection, there is still a critical need for therapeutics and vaccines, with current treatment options only providing supportive care.
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Infection

Nucleoside prodrugs for viral infections disclosed in Gilead patent

March 21, 2025
Gilead Sciences Inc. has divulged nucleoside prodrugs reported to be useful for the treatment of viral infections.
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Antibodies attacking virus cell
Immune

Astrazeneca enters multispecific antibody collaborations with CEPI, Harbour Biomed

March 21, 2025
CEPI is partnering with Astrazeneca plc to advance VHH-based multispecific antibodies targeting influenza, while Harbour Biomed Ltd. has entered into a global strategic collaboration with Astrazeneca to discover and develop next-generation multispecific antibodies for immunology, oncology and other diseases.
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IV drips

Taimed’s long-acting HIV treatment offers daily ART alternative

March 20, 2025
By Tamra Sami
Taimed Biologics Inc.’s TMB-365/TMB-380 long-acting combination of broadly neutralizing antibodies regimen for HIV maintenance could reshape HIV treatment management, offering a viable alternative to daily combination antiretroviral therapy (cART), the Taipei-based company said after reporting on phase IIa results.
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Toilets could be the next big health device: Medical Korea 2025

March 20, 2025
By Marian (YoonJee) Chu
Seung-min Park, professor at Nanyang Technological University and cofounder of Kanaria Health, is working to manufacture smart bidets that can capture biomarker data from urine and stool automatically and enable continuous monitoring.
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Infection

Revagenix describes new aminoglycosides to treat bacterial infections

March 20, 2025
Revagenix Inc. has identified aminoglycosides reported to be useful for the treatment of bacterial infections.
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Photo of child in bed hugging teddy bear
Inflammatory

COVID-19 and Epstein-Barr cause inflammatory shock in children

March 20, 2025
By Mar de Miguel
Multisystem inflammatory syndrome in children (MIS-C), a serious disorder that develops after SARS-CoV-2 infection, could arise from latent infection of another pathogen, the Epstein-Barr virus (EBV). Researchers at Charité – Universitätsmedizin Berlin and the German Rheumatology Research Center (DRFZ) have linked the inflammatory effect of this co-infection with transforming growth factor β (TGF-β), ruling out the possibility that MIS-C is caused by an autoimmune reaction, or persistence of the coronavirus in the body.
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