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Home » Topics » Disease categories and therapies » Inflammatory

Inflammatory
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Knee pain illustration

Shionogi, Grünenthal ink licensing deal worth $525M for injectable osteoarthritis pain drug

Aug. 9, 2022
By Tamra Sami
Shionogi & Co. Ltd. has in-licensed Japan rights to Grunenthal GmbH’s intra-articular injectable, resiniferatoxin, for the treatment of pain associated with osteoarthritis of the knee. Currently in phase III trials, RTX is a transient receptor potential vanilloid 1 agonist, which can reversibly desensitize TRPV1-expressing nociceptors. This mechanism may result in long-lasting pain relief.
Read More
Knee pain illustration

Shionogi, Grünenthal ink licensing deal worth $525M for injectable osteoarthritis pain drug

Aug. 5, 2022
By Tamra Sami
Shionogi & Co. Ltd. has in-licensed Japan rights to Grunenthal GmbH’s intra-articular injectable, resiniferatoxin, for the treatment of pain associated with osteoarthritis of the knee. Currently in phase III trials, RTX is a transient receptor potential vanilloid 1 agonist, which can reversibly desensitize TRPV1-expressing nociceptors. This mechanism may result in long-lasting pain relief.
Read More

Gilead buys UK immunology biotech Mirobio for $405M

Aug. 4, 2022
By Richard Staines
Gilead Sciences Inc. has bought the privately owned U.K. biotech Mirobio Ltd., paying $405 million for the Oxford-based firm and its checkpoint agonists to treat autoimmune diseases. Foster City, Calif.-based Gilead will gain Mirobio’s discovery platform and entire portfolio of immune inhibitory receptor agonists.
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Whole body cellular function recovery in pigs after death

Aug. 4, 2022
A new system for restoring cell function and tissues in mammals after death could expand the availability of organs for transplantation. The research also opens up a previously unexplored field of research in the molecular and cellular mechanisms triggered after death, an area of potential significance, since it covers different biological processes with multiple applications.
Read More
IPO puzzle pieces

Inventisbio nets ¥2.08B in Shanghai IPO; shares plunge 15.6% on debut

Aug. 2, 2022
By Doris Yu
Inventisbio Co. Ltd. has raised ¥2.084 billion (US$296 million) in an IPO on Shanghai’s STAR Market priced at ¥18.12 per share, though its stock saw a disappointing debut, opening at ¥14 per share on the first trading day July 25 and closing at $15.29, for a drop of 15.6%. The stock closed Aug. 1 at ¥14.42.
Read More
Arthritis pain illustration

Apollo brings Cambridge-developed camoteskimab back to UK in $89M deal with Avalo

Aug. 1, 2022
By Richard Staines
Apollo Therapeutics Group Ltd. has bought worldwide rights to Avalo Therapeutics Inc.’s anti-IL-18 antibody, camoteskimab, in a deal worth up $89 million, taking on development of the early stage drug for arthritis and potentially other diseases.
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IPO puzzle pieces

Inventisbio nets ¥2.084B in Shanghai IPO; shares plunge 15.6% on debut

Aug. 1, 2022
By Doris Yu
Inventisbio Co. Ltd. has raised ¥2.084 billion (US$296 million) in an IPO on Shanghai’s STAR Market priced at ¥18.12 per share, though its stock saw a disappointing debut, opening at ¥14 per share on the first trading day July 25 and closing at $15.29, for a drop of 15.6%. The stock closed Aug. 1 at ¥14.42.
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Yoonsun Yang, founder, president and CEO of Medipost and Antonio Lee, head of global operations and corporate development.
Newco news

Korea’s Medipost builds US, Japan presence for umbilical cord blood stem cells

July 26, 2022
By Tamra Sami
South Korea’s Medipost Co. Ltd. is gearing up for phase III trials in the U.S. of its stem cell therapy, Cartistem, an allogeneic human umbilical cord blood-derived mesenchymal stem cell therapy for treatment of knee articular damage in patients with osteoarthritis.
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Nonessential but critical, tyrosine plays key role in nutrient sensing

July 26, 2022
Yoonsun Yang, founder, president and CEO of Medipost and Antonio Lee, head of global operations and corporate development.
Newco news

Korea’s Medipost builds US, Japan presence for umbilical cord blood stem cells

July 25, 2022
By Tamra Sami
South Korea’s Medipost Co. Ltd. is gearing up for phase III trials in the U.S. of its stem cell therapy, Cartistem, an allogeneic human umbilical cord blood-derived mesenchymal stem cell therapy for treatment of knee articular damage in patients with osteoarthritis.
Read More
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