Solid Biosciences Inc. already has its own Duchenne muscular dystrophy program, but with some new investment money it is plunging into a collaboration with Ultragenyx Pharmaceutical Inc. to co-create another program. The two will collaborate on developing and commercializing new gene therapies for treating Duchenne muscular dystrophy as Novato, Calif.-based Ultragenyx is investing $40 million in Solid.
A Chinese study is the first to identify fibroblast activation protein (Fap) as an osteogenic suppressor that could be targeted to prevent osteoporosis and has shown that osteolectin, a bone glycoprotein that binds calcium, is an endogenous Fap inhibitor promoting bone mineralization.
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