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BioWorld - Saturday, April 25, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/Psychiatric

Promis selects lead vaccine candidate against synucleinopathies

Jan. 22, 2024
Promis Neurosciences Inc. has selected a lead vaccine candidate, PMN-400, against synucleinopathies, including multiple system atrophy, Parkinson’s disease and Lewy body dementia.
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Neurology/Psychiatric

Endocannabinoid reuptake inhibitor SYT-510 granted EU IND

Jan. 19, 2024
Synendos Therapeutics AG has received approval from the European Medicines Agency (EMA) to initiate a first-in-human trial of its lead asset, SYT-510, a first-in-class inhibitor that modulates a newly identified drug target in the endocannabinoid system (ECS) to restore healthy brain physiology.
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Neurology/Psychiatric

Rogdi(-/-) mouse recapitulates symptoms of Kohlschütter-Tönz syndrome

Jan. 19, 2024
Researchers from Université de Strasbourg and affiliated organizations presented new mouse...
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Stalicla’s series B adds $17.4M for trials in substance abuse disorders, ASD

Jan. 19, 2024
By Nuala Moran
Stalicla SA announced the first close of a series B round at $17.4 million, which provides the means to complete preparations for both a phase III trial of the lead program, STP-7, in the treatment of cocaine misuse disorder, and of a phase II trial of STP-1 in autism spectrum disorder (ASD).
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Girl in wheelchair

Step Rett up: Acadia’s Daybue comes on strong as others in the works, too

Jan. 18, 2024
By Randy Osborne
After the U.S. FDA granted clearance in March 2023, sales began promptly of Acadia Pharmaceuticals Inc.’s new Rett syndrome therapy, Daybue (trofinetide), and questions during the recent J.P. Morgan Healthcare Conference in San Francisco had to do with – among other matters – sales guidance from the firm, which is hardly alone in seeking treatments for the disease. Other players include Anavex Life Sciences Corp., Neurogene Inc. and Taysha Gene Therapies Inc.
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FDA issues complete response letter to Satsuma for migraine NDA over CMC issues

Jan. 18, 2024
By Tamra Sami
The U.S. FDA issued a complete response letter to Shin Nippon Biomedical Laboratories Ltd.’s U.S. subsidiary, Satsuma Pharmaceuticals Inc., for its NDA for dihydroergotamine nasal powder (STS-101) for acute treatment of migraine, with or without aura, in adults. Shin Nippon acquired Satsuma for $220 million in April 2023 and gained rights to STS-101.
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Niura neurodiagnostic
Patents

Niura’s neurodiagnostic earbuds also give personalized music recommendations

Jan. 18, 2024
By Simon Kerton
A team of inventors predominantly based in the state of New York are seeking patent protection for an earbud system that integrates real-time electroencephalography (EEG) monitoring with audio playback. Using specialized silicone electrodes, it captures and interprets EEG data, serving as a passive and continuous tool for screening neurological conditions.
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Neurology/Psychiatric

Mainline Biosciences discovers new tachykinin NK1 receptor antagonists

Jan. 18, 2024
Mainline Biosciences (Shanghai) Co. Ltd. has described peptides acting as tachykinin NK1 receptor antagonists reported to be useful for the treatment of pain and opioid dependence.
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Neurology/Psychiatric

Bolden raises funds to advance neurogenesis-promoting antisense oligonucleotides

Jan. 18, 2024
Bolden Therapeutics Inc. has closed a $1.5 million pre-seed convertible note financing. This financing, together with National Institutes of Health (NIH) small business grants, will support preclinical development of Bolden's antisense oligonucleotides to promote neurogenesis.
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Drosophila fruit fly
Endocrine/Metabolic

Loss of UCHL1 triggers diabetic phenotype in Drosophila, study finds

Jan. 18, 2024
Diabetic sensory neuropathy (DSN) is among the most common complications of type 2 diabetes, but the mechanisms behind its pathogenesis are not clear.
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