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BioWorld - Sunday, April 26, 2026
Home » Topics » Disease categories and therapies » Neurology/psychiatric

Neurology/psychiatric
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3D illustration of a nerve cell
Neurology/Psychiatric

TMEM97 as a new therapeutic target for the treatment of neuropathic pain

Jan. 16, 2024
The σ2 receptor (σ2R) has been recently identified as transmembrane protein 97 (TMEM97), and ligands of σ2R/TMEM97 have previously shown the ability to alleviate mechanical hypersensitivity in mouse models of neuropathic pain.
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Illustration of motor neuron connecting to muscle fiber
Neurology/Psychiatric

Toleranzia completes pivotal toxicology study with TOL-2 for myasthenia gravis

Jan. 16, 2024
Toleranzia AB has completed a pivotal toxicology study designed to determine the potential toxicity of TOL-2, a tolerance-inducing recombinant protein being developed for the treatment of myasthenia gravis, when given intravenously for 10 days.
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Medtronic Percept RC

FDA greenlights Medtronic sensing-enabled DBS system

Jan. 12, 2024
By Shani Alexander
Medtronic plc received the greenlight from the U.S. FDA for its latest deep brain stimulation system, the Percept RC. The rechargeable neurostimulator includes the company’s sensing technology which captures data from brain signals and allows for more personalized therapy.
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Neurology/Psychiatric

Acadia Pharmaceuticals discovers new GPR88 agonists

Jan. 12, 2024
Acadia Pharmaceuticals Inc. has described G protein-coupled receptor GPR88 agonists reported to be useful for the treatment of attention deficit hyperactivity disorder (ADHD), substance abuse and dependence, schizophrenia, Tourette syndrome, bipolar disorder, Huntington's disease, Alzheimer's disease and Parkinson's disease.
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Gene editing illustration
Neurology/Psychiatric

DoD grant supports Factor Bioscience's development of gene-edited cell therapies

Jan. 12, 2024
Factor Bioscience Inc. has been awarded a grant by the U.S. Department of Defense to develop next-generation cell therapy candidates using Factor's patented mRNA, cell-reprogramming, and gene-editing technologies.
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New boss in FOS? Xenon featured at JPM; Biohaven also in play

Jan. 11, 2024
By Randy Osborne
Xenon Pharmaceuticals Inc. took to the stage this week at the J.P. Morgan Healthcare Conference to talk up its pipeline, including the phase III program testing XEN-1101 in focal-onset seizures (FOS), due to complete enrollment in the second half of this year. It’s an indication where such other players as Biohaven Ltd. are busy, too. Several million adults are afflicted with FOS in the U.S., with close to a half-million pediatric patients.
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Mhealthcare prognostic
Patents

Mhealthcare bed predicts cognitive and developmental disorders

Jan. 11, 2024
By Simon Kerton
The first patenting from Mhealthcare Inc. describes a patient examination table or bed equipped with a variety of sensors, data from which may be analyzed with trained machine learning models to facilitate risk assessment and diagnosis of non-neurotypical developmental conditions such as autism in infants and young children by predicting cognitive, behavioral, social and developmental outcomes as early as the first three months of life. It is also claimed that the table may be used to diagnose epilepsy and Alzheimer’s disease.
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Neurology/Psychiatric

Neuron23 describes new TYK2 inhibitors for neurological disorders

Jan. 11, 2024
Neuron23 Inc. has identified non-receptor tyrosine-protein kinase TYK2 (JH2 domain) inhibitors reported to be useful for the treatment of neurological disorders.
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Neurology/Psychiatric

Myrobalan to use series A funding for CNS neurorestorative therapies

Jan. 11, 2024
Myrobalan Therapeutics Inc. has completed a $24 million series A funding to support development of neurorestorative therapies for CNS diseases.
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Neurology/Psychiatric

TET1 described as a potential pharmacogenomic target for pain

Jan. 11, 2024
Ten-eleven translocation 1 (TET1) is a member of the TET family of enzymes that promote DNA...
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