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BioWorld - Wednesday, April 29, 2026
Home » Topics » Disease categories and therapies » Ocular

Ocular
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TBK1 inhibition is neuroprotective in optic neuropathies

May 10, 2022

ANGPTL7 as a novel therapeutic target for glaucoma

May 10, 2022

Targeting NMNAT2 confers neuroprotection in glaucoma

May 10, 2022
Antibodies attacking cancer cell

Askgene’s series A adds $20M for cytokine fusion, antibody pipeline

May 9, 2022
By Jennifer Boggs
Askgene Pharma Inc., which less than two weeks ago reported positive initial data from an ongoing phase I/II trial testing its claudin 18.2-targeting candidate, ASKB-589, added $20 million in a series A round, intended to advance the company’s clinical pipeline and support further development of its Smartkine cytokine drug platform.
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Oxurion shares fall 40% on phase II miss in DME

May 9, 2022
By Cormac Sheridan
Shares in Oxurion NV dropped 40.3% percent May 9 on news that one of its two clinical-stage assets, THR-687, failed to demonstrate efficacy in a phase II trial in diabetic macular edema (DME). The candidate, a small-molecule pan integrin receptor antagonist, failed to demonstrate efficacy in Part A of the trial, called Integral, in which treatment-naïve patients received one of two doses of THR-687.
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Targeting NR2E3 is a potential approach to avoid photoreceptor degeneration in retinitis pigmentosa

May 9, 2022
IPO money

Pepgen and B&L join a struggling IPO market

May 6, 2022
By Lee Landenberger
IPOs continue to be sluggish but two companies, Pepgen Inc. and Bausch & Lomb Corp., that began trading May 6 managed to sidestep the turbulence despite having to lower their expectations before the market opened. Pepgen stock (NASDAQ:PEPG) closed at $12.89 per share May 6, up 7.4% on the day. Bausch & Lomb also had a solid IPO launch May 6 as shares (NYSE:BLCO) closed 11.1% upward at $20 each.
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Dana-Farber Cancer Institute synthesizes SRPK1/SRPK2 inhibitors

May 5, 2022
Gold dollar sign

Ashvattha lands $69M series B, Huadong licensing deal

May 3, 2022
By David Ho
Ashvattha Therapeutics Inc. secured $69 million in a series B financing that it said will strengthen its ability to develop hydroxyl dendrimer-based medicines and accelerate efforts to advance its candidates to the clinic.
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Gold dollar sign

Ashvattha lands $69M series B, Huadong licensing deal

April 27, 2022
By David Ho
Ashvattha Therapeutics Inc. secured $69 million in a series B financing that it said will strengthen its ability to develop hydroxyl dendrimer-based medicines and accelerate efforts to advance its candidates to the clinic.
Read More
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