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BioWorld - Wednesday, December 17, 2025
Home » Topics » Drugs » Antibody

Antibody
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Stroke illustration: brain, artery, neurons
Neurology/psychiatric

GPVI inhibitor EMA-601 has unprecedented potency in preclinical ischemic stroke

July 3, 2024
Glycoprotein VI (GPVI) is a platelet collagen receptor involved in platelet activation and an emerging target for treating thrombotic disorders such as ischemic stroke. Data have been presented by University of Würzburg scientists regarding a humanized anti-GPVI Fab antibody, EMA-601, with unprecedented potency in vitro and in vivo.
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Antibodies illustration

Tracon quits work on anti-PD-L1 envafolimab after phase III flop

July 2, 2024
By Tamra Sami
Tracon Pharmaceuticals Inc. is shuttering all development of its subcutaneous PD-L1 antibody, envafolimab, after the pivotal trial failed to meet the primary endpoint in soft tissue sarcoma.
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Antibody pic
Immune

Pharma Foods announces autoimmune disease antibody milestone under Mitsubishi Tanabe collaboration

July 2, 2024
Pharma Foods International Co. Ltd. (PFI) has announced the achievement of a milestone under its licensing agreement with Mitsubishi Tanabe Pharma Corp. for a new investigational therapeutic antibody for autoimmune diseases.
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Pink and orange test tubes
Hematologic

Targed Biopharmaceuticals’ TGD-001 attenuates thrombocytopenia and tissue damage in TTP

June 27, 2024
The heterogenous composition of thrombi limits the efficacy of existing therapies.
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Musculoskeletal

Astrazeneca’s AZD-1163 inhibits autoantigen production in rheumatoid arthritis

June 26, 2024
The generation of anti-citrullinated protein autoantibodies (ACPA) are known key drivers in the pathogenesis of rheumatoid arthritis (RA) and are generated by peptidyl arginine deiminases (PADs).
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Molecule illustration
Neurology/psychiatric

Oblique Therapeutics to utilize KTH’s supercomputer resources for analyzing proteins structures

June 19, 2024
Oblique Therapeutics AB has entered into an agreement with the KTH Royal Institute of Technology to utilize KTH’s supercomputer resources for analyzing protein structures.
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Illustration of intestines with inflammation

Futuregen joins Abbvie in $1.7B inflammatory bowel disease deal

June 18, 2024
By Lee Landenberger
Through a global rights agreement with Futuregen Biopharmaceutical Co. Ltd., Abbvie Inc. continues to build its immunology portfolio to help offset losses from Humira as biosimilars tighten their grip on the mega-blockbuster.
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Illustration of intestines with inflammation

Futuregen joins Abbvie in $1.7B inflammatory bowel disease deal

June 14, 2024
By Lee Landenberger
Through a global rights agreement with Futuregen Biopharmaceutical Co. Ltd., Abbvie Inc. continues to build its immunology portfolio to help offset losses from Humira as biosimilars tighten their grip on the mega-blockbuster.
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Gastrointestinal

Abbvie licenses Futuregen’s next-generation TL1A antibody for inflammatory bowel disease

June 14, 2024
Abbvie Inc. and Futuregen Biopharmaceutical (Beijing) Co. Ltd. have signed a license agreement to develop FG-M701, a next-generation TL1A antibody for the treatment of inflammatory bowel disease.
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

Shaperon signs MOU with Dong-A ST to accelerate development of nanobody-based drugs

June 11, 2024
Hudson Therapeutics Inc., a U.S. subsidiary of Shaperon Inc., has announced the signing of a memorandum of understanding (MOU) between Shaperon and Dong-A ST Co. Ltd. for the development of nanobody-based new drugs.
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