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BioWorld - Friday, September 22, 2023
Home » Topics » Newco news

Newco news
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Illustration of interleukin-2 protein structure
Newco news

Aulos Bioscience raises $20 million in series A to further alternative IL-2 approach

Aug. 21, 2023
By Caroline Richards
No Comments
As a cytokine used in the field of immuno-oncology, interleukin-2 (IL-2) can produce durable and even complete responses in some patients, as well as induce immune memory against tumors. However, its rapid metabolism within the body means it has a short serum half-life, so it needs to be given in high doses, which can trigger severe side effects.
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Dotbio CEO Ignacio Asial with team
Immuno-oncology

Dotbio emerges with $5.6M pre-series A to advance multifunctional antibodies

Aug. 17, 2023
By Tamra Sami
No Comments
Emerging from stealth mode, new immuno-oncology company Dotbio Pte. Ltd. closed an oversubscribed $5.6 million pre-series A round to accelerate development of its multifunctional and intracellular antibody therapies.
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Oncolytic virus concept illustration
Newco news

Viralytics team back together again to develop new oncolytic viruses with Immvirx

Aug. 16, 2023
By Tamra Sami
No Comments
The old Viralytics Ltd. team is back together again in a new company called Immvirx Pty Ltd. that is developing oncolytic viruses to tackle the four most deadly cancers, Immvirx CEO and co-founder Malcolm McColl told BioWorld.
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Dotbio CEO Ignacio Asial with team
Newco news

Dotbio emerges with $5.6M pre-series A to advance multifunctional antibodies

Aug. 15, 2023
By Tamra Sami
No Comments
Emerging from stealth mode, new immuno-oncology company Dotbio Pte. Ltd. closed an oversubscribed $5.6 million pre-series A round to accelerate development of its multifunctional and intracellular antibody therapies.
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Ivy Wang, co-founder and executive vice president, Biocity Biopharmaceutics
Newco news

China’s Biocity expands to US with pipeline of bispecific antibodies and ADCs

Aug. 15, 2023
By Tamra Sami
No Comments
Biocity Biopharmaceutics Co. Ltd. is advancing its pipeline of differentiated, modality-independent therapeutics for oncology that include small molecules, monoclonal and bispecific antibodies, as well as antibody-drug conjugates (ADCs). The Wuxi, China-headquartered company is focused on first-in-class molecules for different modalities that can be combined with other treatments, Biocity Co-founder and Executive Vice President Ivy Wang told BioWorld.
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Ivy Wang, co-founder and executive vice president, Biocity Biopharmaceutics
Newco news

China’s Biocity expands to US with pipeline of bispecific antibodies and ADCs

Aug. 11, 2023
By Tamra Sami
No Comments
Biocity Biopharmaceutics Co. Ltd. is advancing its pipeline of differentiated, modality-independent therapeutics for oncology that include small molecules, monoclonal and bispecific antibodies, as well as antibody-drug conjugates (ADCs). The Wuxi, China-headquartered company is focused on first-in-class molecules for different modalities that can be combined with other treatments, Biocity Co-founder and Executive Vice President Ivy Wang told BioWorld.
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Chromosome with shortened telomeres
Newco news

Telos Biotech’s CAR T-cell enhancer set to resurrect dying field of telomere biology

Aug. 11, 2023
By Caroline Richards
No Comments
Critically shortened telomeres are known to be a key limiting factor in successful CAR T-cell immunotherapy, with cells from older patients tending to have shorter telomeres with reduced dividing capacity. As such, these cells are unable to fully eliminate malignancies and provide durable and persistent protection against cancer. So, what if you could lengthen these DNA-protein structures found at the end of chromosomes during the ex-vivo manufacturing of CAR T cells, i.e., before they are put back into the body, so increasing their potency against disease? Newly-launched firm Telos Biotech – a subsidiary company of Cambrian Bio – believes you can, with its patent-protected recombinant protein, Telovance, promising to shake up the cell therapy field.
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Lungs anatomy
Newco news

Anoat takes aim at alternative chloride channel to treat cystic fibrosis

Aug. 10, 2023
By Caroline Richards
No Comments
With more than 70,000 people living with cystic fibrosis (CF) worldwide, according to the Cystic Fibrosis Foundation, the introduction of CF transmembrane conductance regulator (CFTR) modulator therapies has revolutionized treatment of the disease. However, these drugs are not effective for around 10% of CF patients, driving a significant unmet therapeutic need. One startup hoping to address this is Anoat Therapeutics.
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Dotbio CEO Ignacio Asial with team
Newco news

Dotbio emerges with $5.6M pre-series A to advance multifunctional antibodies

Aug. 9, 2023
By Tamra Sami
No Comments
Emerging from stealth mode, new immuno-oncology company Dotbio Pte. Ltd. closed an oversubscribed $5.6 million pre-series A round to accelerate development of its multifunctional and intracellular antibody therapies.
Read More
Michelle Werner, CEO, Alltrna
Newco news

Alltrna-tive approach in transfer RNA draws $109M series B

Aug. 9, 2023
By Randy Osborne
No Comments
Alltrna Inc. raised $109 million in a series B round to back its work with transfer RNA, with the first targeted indication of stop codon disease: a condition that takes in thousands of rare and common afflictions stemming from nonsense mutations where the amino acid code has been mutated into a “stop” codon, also known as a premature termination codon.
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