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BioWorld - Monday, December 29, 2025
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Hand holding vial of Magtrace

Endomag receives NICE endorsement for Magtrace cancer staging technology

Aug. 25, 2021
By Nuala Moran
LONDON – Endomag Ltd. has received endorsement from the U.K. health technology assessment body NICE, opening the way to broader adoption of its Magtrace non-radioactive cancer staging technology in the National Health Service, and providing backing for commercialization of the system in other markets.
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Drug vials and syringe

Case for COVID-19 booster shots strengthens with data from J&J and UK

Aug. 25, 2021
By Richard Staines
Johnson & Johnson has announced new data supporting use of its COVID-19 vaccine as a booster shot, after separate trial data from the U.K. showed effects of several vaccines waned after six months.
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Green traffic light

Astellas and Fibrogen bag European approval for first-in-class HIF-PH inhibitor

Aug. 24, 2021
By Gina Lee
Less than two weeks after Fibrogen Inc. received an FDA complete response letter for its hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor, Evrenzo (roxadustat), Astellas Pharma Inc. and Fibrogen have won European Commission approval for the drug to treat symptomatic anemia associated with chronic kidney disease (CKD) in adults. The approval, which followed a positive CHMP opinion in June, triggered a $120 million milestone payment from Astellas to Fibrogen. In addition, Fibrogen will receive royalties on EU sales of the drug.
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Surgeons in operating room performing open heart surgery

Report exposes underuse of mechanical circulatory assist devices in France

Aug. 24, 2021
By Bernard Banga
PARIS – The High Authority for Health (HAS) in France recently published a 165-page report on use over 10 years of long term mechanical circulatory assist devices (MCS). HAS conducted this wide-ranging study to review the conditions for the management of MCS devices, technology that has been constantly evolving over the past decade.
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Concept of business partnership

Lightpoint Medical and Telix unite for prostate cancer surgery trials

Aug. 24, 2021
By Catherine Longworth
Lightpoint Medical Ltd. is stepping up commercialization activities and collaborating with Telix Pharmaceuticals Ltd. on radio-guided cancer surgery. The companies plan to initiate prostate cancer clinical trials evaluating Lightpoint’s Sensei with Telix’s investigational prostate cancer single photon emission computed tomography (SPECT) imaging agent TLX599-CDx.
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Brain and DNA

Gene therapy ameliorates androgen receptor-driven neuromuscular disease

Aug. 24, 2021
By Anette Breindl
For most people, neither polyglutamine disorders nor neuromuscular disorders are likely to be among the things they associate with androgen receptor (AR) dysfunction. But the three are indeed linked. And researchers have reported new insights into the nature of those links that could lead to a treatment for spinal and bulbar muscular atrophy, and possibly other disorders linked to AR signaling dysfunction.
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Diagram

Weak magnetic fields boost formation of new blood vessels using mesenchymal stromal cells

Aug. 19, 2021
By Bernard Banga
PARIS – Magnetic fields can be used to stimulate blood vessel growth, according to a new study published in Science and Technology of Advanced Materials. The discovery, by researchers from the University of Lisbon in Portugal, could lead to new treatments for cancer and help regenerate tissues that have lost their blood supply.
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Patient given oral swab

High viral loads found in people infected with Delta variant despite being vaccinated

Aug. 19, 2021
By Nuala Moran
LONDON – The latest data from the large-scale randomized U.K. COVID-19 infection survey confirm vaccines are less effective against the Delta variant of SARS-CoV-2 that is now dominant across the U.S., Europe and elsewhere in the world.
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COVID-19 vaccine vials on conveyor belt

COVID-19 vaccines vs. Delta: Study shows lower effectiveness against variant and higher viral load despite vaccination

Aug. 18, 2021
By Nuala Moran
LONDON – The latest data from the large-scale randomized U.K. COVID-19 infection survey confirm vaccines are less effective against the Delta variant of SARS-CoV-2 that is now dominant across the U.S., Europe and elsewhere in the world.
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Silhouette of head, brain

Stress hormones affect brain plasticity via distinct mechanisms

Aug. 18, 2021
By Anette Breindl
Researchers have shown that glucocorticoids, a type of steroid hormones, target both neuroplasticity-related genes and genes related to ciliary function in the brain. However, the effects on the different processes are mediated via different receptors, and in response to different stimuli. A study investigated the specific targets of glucocorticoids, giving new insights into the biological mechanisms of stress adaptations, and how they are linked to neural plasticity.
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