Defence Therapeutics Inc. has contracted Transbiotech Biotechnology Research and Transfer Center to test the potency of the company’s cellular anticancer ARM vaccine in animals with pre-established pancreatic tumors.
Thryv Therapeutics Inc. has announced the closing of a $5 million convertible note investment, the proceeds of which will be used to accelerate development of its pipeline, including preclinical programs in anaplastic thyroid carcinoma and atrial fibrillation.
Shanghai Haiyan Pharmaceutical Technology Co. Ltd. and Yangtze River Pharmaceutical Group have jointly developed S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
Terminal nucleotidyltransferase 4B (TENT4B; PAPD5) inhibitors have been described in a Childrens Medical Center Corp. patent. As such, they are reported to be useful for the treatment of cancer, osteoarthritis, macular degeneration, hepatitis B, pulmonary fibrosis, diabetes, pontocerebellar hypoplasia and cardiovascular disorders, among others.
Researchers from Xinhua Hospital have published data from a study that aimed to assess the role of CEBPG, an important regulator of tumor development, in the progression of ovarian cancer (OC).
Despite the title of the Sunday, June 4 lead-off presentation at the American Society of Clinical Oncology (ASCO) meeting in Chicago, there was little room left for doubt about the increasingly important place of artificial intelligence (AI) in drug development. The program, Artificial Intelligence for Drug Development: Fad or Future, ultimately pointed to a positive future, with the only faddish part being discarded approaches that no longer work.
Researchers at Abbvie Inc. and Calico Life Sciences LLC have described protein tyrosine phosphatase inhibitors, particularly tyrosine-protein phosphatase non-receptor type 2 (PTPN2; TCPTP) and/or PTPN1 (PTP-1B), reported to be useful for the treatment of non-small-cell lung cancer (NSCLC).
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