Wigen Biomedicine Technology (Shanghai) Co. Ltd. has patented poly(ADP-ribose) polymerase (PARP) inhibitors, particularly PARP-1, reported to be useful for the treatment of cancer.
Kayothera Inc. and Princeton University have identified aldehyde dehydrogenase (ALDH) inhibitors reported to be useful for the treatment of cancer, type 2 diabetes and metabolic disease, as well as for male contraception.
Essa Pharma Inc. has divulged androgen receptor antagonists reported to be useful for the treatment of metastatic castration-resistant prostate cancer.
An AU$300,000 grant from The Australian Pancreatic Cancer Foundation (Pankind) will support research at the Garvan Institute of Medical Research into the use of a porcupine-targeting molecule for pancreatic cancer.
It doesn't happen very often, but the same scientists who participated in the discovery of a signaling pathway can also undo their findings and go back to square one. “When we discovered Hippo signaling, some 20 years ago, everybody was excited about it because we thought it was going to explain a big part of how growth is regulated. Now it turns out that it is not what it is doing,” Georg Halder told BioWorld.
Sunshine Biopharma Inc. has entered into a collaboration agreement with a leading lipid nanoparticle (LNP) formulation company to advance the development of Sunshine's mRNA-based anticancer macromolecule, K1.1.
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