Investigators from the Thomas Jefferson University have presented a case report of a 27-year-old pregnant patient in whom cystic hygroma, extensive anasarca, bilateral pleural effusions, ascites, abnormally curved sacrum and hydrocephalus with parenchymal volume loss, among others were detected by prenatal imaging during pregnancy (onset was at about 21 weeks of gestation).

Researchers from Biohaven Pharmaceutical Holding Co. Ltd. presented preclinical data for...

Quralis Corp. has launched a program that targets UNC13A mis-splicing, a critical genetic alteration...

A new study has uncovered a potential link between RNA regulation and the development of neurodegenerative diseases, such as Parkinson’s disease and dementia. This work, conducted by researchers at the University of Nottingham, used a combination of microscopy and machine learning techniques to examine the role of N6-methyladenosine modification of RNA (m6A) in the human brain.

Researchers from Zhengzhou University presented the synthesis and preclinical evaluation of hybrids...

Vesigen Therapeutics Inc. has been awarded a grant by the Friedreich’s Ataxia Research Alliance (FARA) to develop a targeted genome editing therapeutic strategy for Friedreich’s ataxia.

High levels of bilirubin exacerbated damage to neurons in the brain caused by a stroke by binding to the TRPM2 channel, which helped regulate cell death among other processes. The research, led by Shanghai Jiao Tong University School of Medicine and the University of Toronto and published March 14, 2023, in Neuron, showed that blocking the binding site for bilirubin in a mouse model led to improvements in neurotoxicity suggesting some potential for the development of new stroke therapeutics.