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Other news to note for Nov. 2, 2022

Nov. 2, 2022
Additional early-stage research and drug discovery news in brief, from: Hinova, Marengo, Rakovina, Sporos Biodiscovery.
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Cancer

Hainan Sparkle Therapeutics discovers new USP1 inhibitors

Nov. 2, 2022
Hainan Sparkle Therapeutics Co. Ltd. has described ubiquitin carboxyl-terminal hydrolase 1 (USP1) inhibitors reported to be useful for the treatment of cancer.
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Neurology/Psychiatric

Shandong Luye Pharmaceutical presents new compounds for Parkinson’s disease

Nov. 2, 2022
Shandong Luye Pharmaceutical Co. Ltd. has divulged cannabidiol prodrugs reported to be useful for the treatment of cancer, tremor, epilepsy, anxiety disorder, inflammatory disorders, pain, multiple sclerosis and Parkinson's disease, among others.
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Cancer

Lifearc describes new ULK inhibitors

Nov. 2, 2022
Lifearc has identified pyrimidine compounds acting as serine/threonine-protein kinase ULK inhibitors reported to be useful for the treatment of chronic myeloid leukemia.
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Cancer

University of Basel divulges new PI3K inhibitors

Nov. 2, 2022
The University of Basel has synthesized triazine derivatives acting as phosphatidylinositol 3-kinase (PI3K) inhibitors reported to be useful for the treatment of cancer, neurological and immunological disorders.
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Cancer

Rhizen Pharmaceuticals and Incozen Therapeutics patent new PARP inhibitors

Nov. 2, 2022
Rhizen Pharmaceuticals SA and Incozen Therapeutics Pvt. Ltd. have disclosed salts of NAD+ ADP-ribosyltransferase poly [ADP-ribose] polymerase (PARP) inhibitors reported to be useful for the treatment of cancer, bone, cardiovascular, immunological, inflammatory and respiratory disorders, metabolic diseases and thrombosis.
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Cancer cells
Immuno-oncology

Turnstone receives IND clearance for phase I trial of TIDAL-01 for solid tumors

Nov. 2, 2022
Turnstone Biologics Corp. has received IND clearance from the FDA for the company's lead selected tumor-infiltrating lymphocyte (TIL) therapy program, TIDAL-01.
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DNA illustration
Biomarkers

Researchers identify SPTSSA gene variants to impact hereditary spastic paraplegia risk

Nov. 2, 2022
The Undiagnosed Diseases Network uncovered three unrelated individuals with mutations in the gene encoding serine palmitoyltransferase small subunit A (SPTSSA).
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Infection

Epivax to identify epitopes as part of CEPI-funded betacoronavirus vaccine project with Intravacc

Nov. 2, 2022
Epivax Inc. is taking part in a new project with Intravacc BV, funded by CEPI (Coalition for...
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Biomarkers

MUC22 as potential biomarker of resistance to SARS-CoV-2 infection

Nov. 2, 2022
While elderly people are at a significantly higher risk of developing severe and lethal forms of...
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