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Cancer

New protein kinase inhibitors synthesized at Tsd Life Sciences

Sep. 20, 2022
Tsd Life Sciences Co. Ltd. has discovered imidazopyridine derivatives acting as protein kinase inhibitors and reported to be useful for the treatment of cancer.
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Infection

Biopharma identifies new combretastatin derivatives

Sep. 20, 2022
Biopharma Corp. has described triazolyl combretastatin derivatives reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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Cancer

Korea University Research and Business Foundation presents new DPP4 inhibitors

Sep. 20, 2022
Korea University Research and Business Foundation (KURBF) has identified adamantyl derivatives acting as dipeptidyl peptidase 4 (DPP4; CD26) inhibitors reported to be useful for the treatment of cancer, autoimmune disease, Parkinson's disease, nonalcoholic steatohepatitis (NASH), rheumatoid arthritis, aortic valve stenosis and cerebrovascular and dermatological disorders.
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Liver organoid
Drug Design, Drug Delivery & Technologies

Emulate launches new AAV transduction application for Liver-Chip

Sep. 20, 2022
Emulate Inc. has launched a new adeno-associated virus (AAV) transduction application for the Liver-Chip that enables gene therapy researchers to test the delivery efficiency and safety of AAV vectors in a validated, human-relevant model of the liver and get results in weeks.
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Drug capsule spilling onto brain
Neurology/Psychiatric

NEK6 identified as a novel therapeutic target in ALS and FTD

Sep. 20, 2022
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases, with clinical, pathological and genetic overlap, without effective therapy.
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Triatomine insect on target
Infection

AN-15368 demonstrates efficacy in rhesus macaques infected with T. cruzi

Sep. 20, 2022
Researchers from Anacor Pharmaceuticals Inc. and Pfizer Inc. have published preclinical data for the novel benzoxaborole prodrug AN-15368, being developed for the treatment of Chagas disease.
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Immuno-oncology

Netris collaborates with Orano and CLB to develop antibody-radio conjugates for cancer

Sep. 20, 2022
Netris Pharma SAS has entered into a scientific collaboration agreement with Orano SA and the Centre Léon Bérard (CLB) to develop novel antibody-radio conjugates for the treatment of cancer.
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COVID-19 research illustration
Infection

Bacteriophage-based, mucosal, needle-free COVID-19 vaccine protects against challenge in vivo

Sep. 20, 2022
The development of needle-free mucosal vaccines for SARS-CoV-2 would be advantageous, potentially reducing viral acquisition as well as transmission.
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Neurology/Psychiatric

Campbell Neurosciences reports findings with Campbellcell in animal model of bipolar disorder

Sep. 20, 2022
Therapeutic Solutions International Inc. has announced promising data on the use of Campbellcell for treatment of bipolar disorder by the company's suicide prevention-based spin-off Campbell Neurosciences Inc.
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/Psychiatric

ADS-024 restores movement in mice with PD

Sep. 20, 2022
Parkinson’s disease (PD) is one of those diseases in which bacteria may play a role in disease progression.
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