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BioWorld - Monday, August 3, 2026
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Immuno-oncology

KZR-540 blocks PD-1 expression and inhibits tumor growth in vivo

Nov. 18, 2022
Preclinical studies have found that targeting...
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Cancer

Kinensus designs and tests AXL/MER inhibitors

Nov. 18, 2022
The TAM family of receptor tyrosine kinases...
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Immuno-oncology

Cytomx and Regeneron collaborate on conditionally activated bispecific cancer therapies

Nov. 18, 2022
Cytomx Therapeutics Inc. and Regeneron...
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Brain with handshake and cityscape
Neurology/Psychiatric

Attralus and Ossianix agree to use TXP1 brain shuttle to deliver AT-04 for neurodegenerative diseases

Nov. 18, 2022
Attralus Inc. and Ossianix Inc. have entered into...
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Immuno-oncology

Encouraging preclinical results reported for ASKG-915, a new cytokine prodrug fusion protein

Nov. 18, 2022
Researchers from Askgene Pharma Inc...
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Liver disease
Gastrointestinal

ID-119031166 improves NASH and liver fibrosis in hamsters

Nov. 18, 2022
ID-119031166 is a non-bile acid farnesoid X...
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Neurons
Neurology/Psychiatric

Intra-DRG administration of RLVT-14-02 effective against neuropathic pain in preclinical model

Nov. 18, 2022
Neuropathic pain (NP) is caused by damage or...
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Cancer

No, Hippo doesn’t control normal organ growth

Nov. 18, 2022
By Mar de Miguel
It doesn't happen very often, but the same scientists who participated in the discovery of a signaling pathway can also undo their findings and go back to square one. “When we discovered Hippo signaling, some 20 years ago, everybody was excited about it because we thought it was going to explain a big part of how growth is regulated. Now it turns out that it is not what it is doing,” Georg Halder told BioWorld.


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Illustration of dinosaurs with various combinations of horns and spiky backs.
Genetic/Congenital

In assessing shared genetic risk, love can look like pleiotropy

Nov. 18, 2022
By Anette Breindl
Social scientists are well aware of the consequences of what’s called assortative mating, that is, the fact that marriages tend to occur between people who are similar in things such as interests, social status, education and wealth. Biologists, on the other hand, have tended to ignore it. “When studying the genetic underpinnings of correlated traits, “for mathematical convenience, we’ve assumed basically for forever that mating is random,” Richard Border told BioWorld. “Which it isn’t.”
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Nanoparticles in cancer cells.
Cancer

Sunshine Biopharma collaborates to advance LNP formulation of its antineoplastic mRNA K1.1

Nov. 17, 2022
Sunshine Biopharma Inc. has entered into a collaboration agreement with a leading lipid nanoparticle (LNP) formulation company to advance the development of Sunshine's mRNA-based anticancer macromolecule, K1.1.
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