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BioWorld - Tuesday, December 16, 2025
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Endocrine/metabolic

Kexing Biopharm highlights progress across pipeline

Jan. 24, 2025
Kexing Biopharm Co. Ltd. has outlined progress in its cachexia and autoimmune pipelines, built upon its Kx-Body antibody technology platform and Kx-Fusion fusion protein technology platform.
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Illustration of antibody carrying radioactive isotope
Cancer

Ymmunobio and Paul Scherrer Institute advance radioactive loaded antibodies

Jan. 24, 2025
Ymmunobio AG, in collaboration with the Paul Scherrer Institute, has received an Innosuisse grant to develop innovative radioactive loaded antibodies for the treatment and diagnosis of solid tumors based on Ymmunobio’s proprietary YB-800.
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Cancer

PRMT5 inhibitors show effects against rare tumors of the salivary glands

Jan. 24, 2025
Adenoid cystic carcinoma (ACC) is a rare malignancy of the secretory glands with a high tendency to invade adjacent tissue and spread to the lung, bone or liver. No treatments other than surgery or radiotherapy are available, so new therapeutic strategies are urgently needed.
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Illustration of lungs in the night sky with molecular structures as stars
Cardiovascular

Lysosomes, NCOA7 on the scene of pulmonary arterial hypertension

Jan. 24, 2025
By Xavier Bofill Bruna
Researchers from the University of Pittsburgh School of Medicine have linked pulmonary arterial hypertension (PAH), a progressive disease characterized by blood vessel remodeling, with lysosomal dysfunction and sterol metabolism. They reported their results on Jan. 23, 2025, in Science.
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3D illustration of human digestive system

More China ADCs: Arrivent gets GI cancer drug in $1.2B Lepu deal

Jan. 23, 2025
By Marian (YoonJee) Chu
A year after its $175 million IPO in 2024, Arrivent Biopharma Inc. picked up rights to develop and commercialize Lepu Biopharma Co. Ltd.’s antibody-drug conjugate (ADC) candidate, MRG-007, worldwide excluding the greater China region.
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Cancer

Ohio State University discovers new radiosensitizers

Jan. 23, 2025
Ohio State University has described NADH-ubiquinone oxidoreductase (complex I) inhibitors acting as radiosensitizers for radiation therapy reported to be useful for the treatment of cancer.
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Cancer

New PI3K inhibitors disclosed in Forschungsverbund Berlin patent

Jan. 23, 2025
Forschungsverbund Berlin eV has divulged phosphatidylinositol 4-phosphate 3-kinase (PI3K) inhibitors, particularly PI3K C2 domain-containing subunit β (PIK3C2B) inhibitors, reported to be useful for the treatment of cancer, diabetes, X-linked myotubular myopathy and cardiovascular disorders.
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Cancer

Shanghaitech University describes new DNMT3A inhibitors

Jan. 23, 2025
Shanghaitech University has identified thiazolidinedione compounds acting as DNA methyltransferase 3A (DNMT3A) inhibitors reported to be useful for the treatment of acute myeloid leukemia and overgrowth syndrome.
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Cancer

Hangzhou Healthytide Biotechnology divulges new peptoids targeting integrins α5β1, αvβ5 and αvβ6

Jan. 23, 2025
Hangzhou Healthytide Biotechnology Co. Ltd. has synthesized peptoid compounds targeting integrin α5β1 and/or integrin αvβ5 and/or αvβ6 reported to be useful for the diagnosis and treatment of cancer.
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Gynecology/obstetrics

Celmatix patents new FSH receptor agonists to treat infertility

Jan. 23, 2025
Celmatix Inc. has disclosed FSH receptor (FSHR) agonists reported to be useful for the treatment of infertility.
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