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Home » Topics » Disease categories and therapies » Aging

Aging
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Illustration showing parts of a kidney nephron
Biomarkers

FFAR4 as biomarker of glomerular injury and aging

June 4, 2025
No Comments
Researchers have discovered that reduced expression of the free fatty acid receptor 4 (FFAR4) is a biomarker of podocyte injury and aging, as well as a therapeutic target. Podocyte injury leads to progression of glomerular disease and aging, but the underlying mechanisms are poorly understood.
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Aimedbio’s ₩51B pre-IPO round to fuel new cancer ADCs

June 3, 2025
By Marian (YoonJee) Chu
No Comments
Samsung Medical Center spinoff Aimedbio Inc. announced raising ₩51.1 billion (US$37.15 million) in pre-IPO funding to advance its portfolio of clinical and preclinical antibody-drug conjugate (ADC) candidates.
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Aimedbio’s ₩51B pre-IPO round to fuel new cancer ADCs

June 2, 2025
By Marian (YoonJee) Chu
No Comments
Samsung Medical Center spinoff Aimedbio Inc. announced raising ₩51.1 billion (US$37.15 million) in pre-IPO funding to advance its portfolio of clinical and preclinical antibody-drug conjugate (ADC) candidates.
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Art concept for decoding DNA
Aging

Epigenetics tells the story of aging blood cells

May 28, 2025
By Mar de Miguel
No Comments
The variety of blood cells decreases with age. Some are lost, while others become dominant, leading to a loss of functional diversity. This, in turn, weakens the immune system in older individuals and increases the risk of developing hematological diseases. Scientists in Barcelona have developed a method based on DNA methylation that works like a barcode. EPI-Clone identifies and traces the origin of blood cells to measure the complexity of these clones in aging humans and mice.
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Human aging illustration

Juvenescence's $76M+ to advance CD38, ketone drugs to clinic

May 21, 2025
By Nuala Moran
No Comments
Anti-aging specialist Juvenescence Ltd. reached the first close of its series B-1 at $76 million and said it is on course to close the round at $150 million in the third quarter of 2025. “The reason for the first close and not waiting for the very end is just so we can start to move the pipeline forward,” said Richard Marshall, CEO. “We’ve got molecules in and waiting to go, so the sooner we can get going on those, the better,” he told BioWorld.
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Apimeds Pharmaceuticals raises $13.5M from NYSE American debut

May 20, 2025
By Marian (YoonJee) Chu
No Comments
Apimeds Pharmaceuticals US Inc. (APUS), a subsidiary of Kospi-listed Inscobee Inc., said May 12 that it raised $13.5 million from its stock sale on the NYSE American exchange May 9 through an offering of 3.375 million shares at $4 per share. Hopewell, N.J.-based APUS is the second pharmaceutical company with Asian ties to float shares on the U.S. market this year.
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Apimeds Pharmaceuticals raises $13.5M from NYSE American debut

May 14, 2025
By Marian (YoonJee) Chu
No Comments
Apimeds Pharmaceuticals US Inc. (APUS), a subsidiary of Kospi-listed Inscobee Inc., said May 12 that it raised $13.5 million from its stock sale on the NYSE American exchange May 9 through an offering of 3.375 million shares at $4 per share. Hopewell, N.J.-based APUS is the second pharmaceutical company with Asian ties to float shares on the U.S. market this year.
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Illustration showing cross section of skeletal muscle
Musculoskeletal

Lack of NAD does not alter muscle function or accelerate aging

May 5, 2025
By Mar de Miguel
No Comments
Adult skeletal muscle tolerates a lack of the coenzyme nicotinamide adenine dinucleotide (NAD), according to a study led by scientists at the University of Copenhagen. Their results suggest that adverse effects previously associated with congenital NAD depletion in this tissue may be due to impaired muscle development rather than to a deficiency of this molecule.
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Illustration of women's reproductive organs
Aging

Ovarian aging research gives insight into aging in multiple tissues

April 25, 2025
By Anette Breindl
“Just simply getting old, from age 50 to 75, increased risk for Alzheimer’s disease by 100-fold, which really dwarfed 10-fold increase in risk, conferred by all known risk factors combined, including APOE genotype, being a female, hypertension, smoking, physical inactivity and diabetes.
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Illustration of women's reproductive organs
Aging

Ovarian aging research gives insight into aging in multiple tissues

April 24, 2025
By Anette Breindl
“Just simply getting old, from age 50 to 75, increased risk for Alzheimer’s disease by 100-fold, which really dwarfed 10-fold increase in risk, conferred by all known risk factors combined, including APOE genotype, being a female, hypertension, smoking, physical inactivity and diabetes. And this trend stays true for almost all chronic diseases,” Yousin Suh told her audience earlier this week during a talk for the NIH Director’s Wednesday Afternoon Lecture Series.
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