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Home » Topics » Disease categories and therapies » Aging

Aging
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Zebrafish
Aging

Drug screening using zebrafish wrn-KO mutant model identifies geroprotective agent

Feb. 10, 2025
Researchers from Fudan University and Southwest University published data from a study that detailed the development of a novel vertebrate model suitable for high-throughput screening of potential antiaging compounds.
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Illustration of a pink head and blue head
Neurology/psychiatric

The brain ages and survives differently in females and males

Jan. 29, 2025
By Mar de Miguel
The way the brain ages is not the same in women and men. A study in mice has observed differences in the expression of the maternal and paternal X chromosomes that could explain variation in brain aging between the sexes and a faster deterioration in some women. Another study has discovered different survival strategies in the microglial cells of females and males. Both studies highlight sex differences that could have implications for several age-related neurological disorders, such as Alzheimer’s or Parkinson’s.
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Linkgevity founders Carina Kern, CEO (left), and Serena Kern-Libera, COO (right), at the Francis Crick Institute in London
Nephrology

Linkgevity targets aging as it joins startup accelerator KQ Labs

Jan. 28, 2025
By Nuala Moran
Newco Linkgevity Ltd. has won backing from the KQ Labs accelerator program at the Francis Crick Institute in London, enabling it to take forward the lead program, an anti-necrotic drug for treating acute kidney injury, and to further develop its AI-driven system for identifying aging-related therapeutic targets. Alongside access to the Crick’s expertise in translational research and in shaping academic science to make it investible, companies joining KQ Labs receive an equity investment.
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Linkgevity founders Carina Kern, CEO (left), and Serena Kern-Libera, COO (right), at the Francis Crick Institute in London
Newco news

Linkgevity targets aging as it joins startup accelerator KQ Labs

Jan. 24, 2025
By Nuala Moran
Newco Linkgevity Ltd. has won backing from the KQ Labs accelerator program at the Francis Crick Institute in London, enabling it to take forward the lead program, an anti-necrotic drug for treating acute kidney injury, and to further develop its AI-driven system for identifying aging-related therapeutic targets.
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Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 21, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
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Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 15, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
Read More
Tanycytes illuminated and color coded according to their depth in the hypothalamus brain of a mouse
Aging

Map is first step toward healthy brains into old age

Jan. 14, 2025
By Anette Breindl
2024 saw the completion of several cellular-resolution brain maps, including the entire fly brain and a comprehensive connections map of a cubic centimeter of human brain. 2025 began with the addition of another important map. In the Jan. 1, 2025, issue of Nature, researchers from the Allen Institute presented a map of areas and cell types where aging most affected the mouse brain.
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Concept art for targeting cancer

Insilico wins second Menarini deal with oncology candidate

Jan. 13, 2025
By Marian (YoonJee) Chu
Insilico Medicine Inc. nabbed a potential $550 million-plus deal with Menarini Group’s Stemline Therapeutics Inc. for an unnamed preclinical small-molecule drug targeting solid tumors, adding to a $500 million deal inked by the duo in January 2024.
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Tanycytes illuminated and color coded according to their depth in the hypothalamus brain of a mouse
Aging

Map is first step toward healthy brains into old age

Jan. 9, 2025
By Anette Breindl
2024 saw the completion of several cellular-resolution brain maps, including the entire fly brain and a comprehensive connections map of a cubic centimeter of human brain. 2025 began with the addition of another important map. In the Jan. 1, 2025, issue of Nature, researchers from the Allen Institute presented a map of areas and cell types where aging most affected the mouse brain.
Read More
Ultrasound photo and pregnancy test on mantle with Christmas garland

Scientists deliver the latest advances in pregnancy health

Jan. 3, 2025
By Mar de Miguel
Around the end of every year, the media reports on pregnancy and women who give birth on the last and first days of the new year. They tell their stories, the names of their babies and the cities where they were born. While 2024 was coming to an end, gynecologists and other researchers finalized their publications to improve the health of women and their babies. The formation of the placenta or the study of preeclampsia are some of the first and last stories that greet and say goodbye to 2024. Those of 2025 will be born soon.
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