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BioWorld - Monday, April 13, 2026
Home » Topics » Disease categories and therapies » Aging

Aging
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Stem cells

ARDD 2025: Hitting rewind, not reset, for in vivo rejuvenation

Aug. 29, 2025
By Anette Breindl
No Comments
At the 12th Aging Research & Drug Discovery (ARDD) Meeting, which is being held this week in Copenhagen, Life Biosciences Inc. announced that it is developing its partial epigenetic reprogramming technology for liver disease as well as optic neuropathies. The company’s chief scientific officer Sharon Rosenzweig-Lipson estimated that its ER-100 would enter clinical trials in early 2026, putting it on track to be the first application of partial epigenetic reprogramming to enter the clinic.
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Dollar sign droplet above test tube
Biomarkers

Boost for Minovia Therapeutics’ mitochondrial biomarkers

Aug. 28, 2025
No Comments
Minovia Therapeutics Ltd. has announced a $350,000 grant from Countdown for a Cure for a research proposal related to the development of novel mitochondrial blood-based biomarkers.
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Illustration of brain degeneration
Aging

MED15 T603 phosphorylation controls SASP production in aging

Aug. 27, 2025
No Comments
Aging is marked by a gradual decline in body function, partly driven by the buildup of senescent cells. These cells stop dividing but release a mix of inflammatory and tissue-remodeling factors, known as the senescence-associated secretory phenotype (SASP).
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Stem cells
Aging

ARDD 2025: Hitting rewind, not reset, for in vivo rejuvenation

Aug. 27, 2025
By Anette Breindl
No Comments
At the 12th Aging Research & Drug Discovery (ARDD) Meeting, which is being held this week in Copenhagen, Life Biosciences Inc. announced that it is developing its partial epigenetic reprogramming technology for liver disease as well as optic neuropathies. The company’s chief scientific officer Sharon Rosenzweig-Lipson estimated that its ER-100 would enter clinical trials in early 2026, putting it on track to be the first application of partial epigenetic reprogramming to enter the clinic.
Read More
G2Gbio CEO Lee Hee-yong (center) commemorates the company’s listing on the Korea Exchange

Microsphere injectables biotech G2Gbio debuts with $38M

Aug. 19, 2025
By Marian (YoonJee) Chu
No Comments
G2Gbio Inc. debuted on the Korea Exchange with a ₩52.2 billion (US$37.7 million) IPO Aug. 14. Nearly half of the funds raised will be used to expand Cheongju-si, South Korea-based G2Gbio’s manufacturing plants and help mass produce sustained-release injectable drug products such as GB-5001, its lead candidate in development as a once-monthly formulation of donepezil (Aricept; Eisai Co. Ltd.) for Alzheimer’s disease.
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G2Gbio CEO Lee Hee-yong (center) commemorates the company’s listing on the Korea Exchange

Microsphere injectables biotech G2Gbio debuts with $38M

Aug. 14, 2025
By Marian (YoonJee) Chu
No Comments
G2Gbio Inc. debuted on the Korea Exchange with a ₩52.2 billion (US$37.7 million) IPO Aug. 14. Nearly half of the funds raised will be used to expand Cheongju-si, South Korea-based G2Gbio’s manufacturing plants and help mass produce sustained-release injectable drug products such as GB-5001, its lead candidate in development as a once-monthly formulation of donepezil (Aricept; Eisai Co. Ltd.) for Alzheimer’s disease.
Read More
Results of lithium orotate vs. lithium carbonate on amyloid-β and tau
Neurology/psychiatric

Lithium could change Alzheimer's care, but not all forms work

Aug. 14, 2025
By Mar de Miguel
No Comments
The difference between the origin of Alzheimer's disease (AD) and its symptoms is an obstacle to finding effective treatments. Scientists focused on amyloid-β (Aβ) plaques and tau aggregates to slow neurodegeneration and cognitive decline. Without identifying what causes AD, approved treatments do not provide much benefit.
Read More
Results of lithium orotate vs. lithium carbonate on amyloid-β and tau
Neurology/psychiatric

Lithium could change Alzheimer's care, but not all forms work

Aug. 7, 2025
By Mar de Miguel
No Comments
The difference between the origin of Alzheimer's disease (AD) and its symptoms is an obstacle to finding effective treatments. Scientists focused on amyloid-β (Aβ) plaques and tau aggregates to slow neurodegeneration and cognitive decline. Without identifying what causes AD, approved treatments do not provide much benefit. However, new findings suggest that restoring lithium levels in the brain could prevent and treat AD. Not just any lithium would work, just the forms that do not bind to Aβ.
Read More
Carotid ultrasound
Aging

UK Biobank project complete, supports research with 100,000 scans

July 17, 2025
By Nuala Moran
No Comments
After a 10-year project and a £60 million (US$80 million) investment, the UK Biobank has completed the whole body scans of 100,000 volunteers and is making the 1 billion images available for researchers worldwide.
Read More
Carotid ultrasound

UK Biobank project complete, supports research with 100,000 scans

July 16, 2025
By Nuala Moran
No Comments
After a 10-year project and a £60 million (US$80 million) investment, the UK Biobank has completed the whole body scans of 100,000 volunteers and is making the 1 billion images available for researchers worldwide.
Read More
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