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Home » Topics » Disease categories and therapies » Aging

Aging
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Illustration of proteins on neurons in the aging brain
Aging

Ketone bodies could clear misfolded proteins in the brain

Dec. 5, 2024
A ketone body, a molecule derived from the metabolism of acids to obtain energy when glucose is not available, could become an effective ally in treating Alzheimer’s or preventing the effects of aging on the brain. A group of scientists at the Buck Institute for Research on Aging have studied the role of β-hydroxybutyrate (βHB) as a signaling metabolite of misfolded proteins by interacting with them and altering their solubility, a mechanism that allows their elimination, as observed in preclinical models.
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Neurophet Aqua

Neurophet wins FDA nod for brain AI software, targets US expansion

Nov. 25, 2024
By Marian (YoonJee) Chu
On the heels of U.S. FDA approval for Neurophet Aqua, an updated version of its artificial intelligence (AI)-based magnetic resonance imaging analysis software for the brain, Neurophet Inc. is preparing for an IPO in 2025 and expansion into U.S. and European markets.
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Silhouettes of women from birth to old age
Aging

Telomir reports findings with Telomir-1 in aging model

Nov. 22, 2024
Telomir Pharmaceuticals Inc. has reported preclinical results from evaluation of Telomir-1 in Caenorhabditis elegans, a well-established model for aging studies. Telomir-1 is a novel small molecule designed to lengthen the DNA’s protective telomere caps, which are crucial in the aging process.
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Aging

EA Pharma discovers new ACMSD inhibitors

Nov. 15, 2024
EA Pharma Co. Ltd. has described 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD) inhibitors reported to be useful for the treatment of age-related issues, as well as inflammatory, metabolic, neurodegenerative, mitochondrial and renal diseases.
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Businessman and IPO virtual screen

Duchembio files for IPO to grow radiopharma business

Nov. 12, 2024
By Marian (YoonJee) Chu
Radiopharmaceutical biotech and contract development and organization firm Duchembio Co. Ltd. filed a securities report to South Korea’s Financial Services Commission Nov. 11, kickstarting the IPO process to list on the Korea Exchange.
Read More
Businessman and IPO virtual screen

Duchembio files for IPO to grow radiopharma business

Nov. 11, 2024
By Marian (YoonJee) Chu
Radiopharmaceutical biotech and contract development and organization firm Duchembio Co. Ltd. filed a securities report to South Korea’s Financial Services Commission Nov. 11, kickstarting the IPO process to list on the Korea Exchange.
Read More
Components of a radiopharmaceutical
KoNECT 2024

Panel discusses radiopharmaceuticals, oral small-molecule drugs for AD

Nov. 5, 2024
By Marian (YoonJee) Chu
A year out from Leqembi’s approval for Alzheimer’s disease (AD), ongoing research coupled with artificial intelligence is advancing both radiopharmaceuticals and small-molecule drugs for AD diagnostics and treatment, speakers at the 2024 KoNECT-MOHW-MFDS conference said.
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Components of a radiopharmaceutical
KoNECT 2024

Panel discusses radiopharmaceuticals, oral small-molecule drugs for AD

Nov. 4, 2024
By Marian (YoonJee) Chu
A year out from Leqembi’s approval for Alzheimer’s disease (AD), ongoing research coupled with artificial intelligence is advancing both radiopharmaceuticals and small-molecule drugs for AD diagnostics and treatment, speakers at the 2024 KoNECT-MOHW-MFDS conference said.
Read More
Time perception clocks
Genetic/congenital

Angiopoietin-2 slows down vascular accelerated aging in progeria

Oct. 23, 2024
By Coia Dulsat
Researchers from the University of Maryland in collaboration with the National Institutes of Health (NIH) and Duke University have identified angiopoietin-2 (Ang2) as a targetable protein to reverse cardiovascular dysfunction in Hutchinson-Gilford progeria syndrome (HGPS).
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Aging

Caraway Therapeutics reports new mucolipin activators

Oct. 21, 2024
Caraway Therapeutics Inc. patents describe new mucolipin (MCOLN; TRPML) activators reported to be useful for the treatment of aging, cancer, ciliopathies, glycogen and lysosomal storage diseases, macular degeneration, neurodegeneration and autosomal dominant polycystic kidney.
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