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In the clinic for Dec. 11, 2024

Dec. 11, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: AC Immune, Affimed, ALX, Arvinas, Atyr, Biomea, Cardiff, Cervomed, Daré, Grin, Ichnos, Immix, Immune-Onc, Keros, Lyell, Immunopharma, Maat, Nanobiotix, Newamsterdam, Nurix, Olema, Pfizer, Recursion, Regeneron, Rigel, Sellas, Sumitomo.
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Appointments and advancements for Dec. 11, 2024

Dec. 11, 2024
New hires and promotions in the biopharma industry, including: Accent, Convergent, EMD Serono, Gen1e, Genesis, Iambic, Incendia, Xaira.
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Other news to note for Dec. 11, 2024

Dec. 11, 2024
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Ascendis, Cimeio, Er-Kim, Johnson, Kyowa, Lava, Neurobiogen, Pfizer, Poseida, Relmada, Roche, Scilex, Semnur.
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Financings for Dec. 11, 2024

Dec. 11, 2024
Biopharmas raising money in public or private financings, including: Cardiff Oncology, Eikonizo, Maia, Novo Nordisk, Orthogon, Renaissthera, Sonnet.
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Illustration of a T cell
Drug design, drug delivery & technologies

Engineered T cells can serve as organ-specific delivery service

Dec. 11, 2024
By Coia Dulsat
Researchers from the University of California San Francisco (UCSF) have successfully replicated the design of regulatory T cells, achieving local targeted immune suppression and protection from CAR T-cell cytotoxicity. Many of the treatments used so far in the context of inflammatory and autoimmune disorders lead to systemic immunosuppression. In this sense, limiting immunosuppression locally to targeted tissues may help overcome systemic toxicity.
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Investment advisers face fraud charges in Biovie trading

Dec. 10, 2024
The U.S. SEC filed charges against David Banister and The Market Analysts Group LLC, which Banister controls, alleging that they conducted a fraudulent scheme to promote long-term investment in Biovie Inc. without disclosing that Banister was actively selling his own shares in the biopharma company.
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Bionomics progresses BNC-210 to phase III in PTSD

Dec. 10, 2024
By Tamra Sami
Bionomics is progressing BNC-210 to phase III trials in post-traumatic stress disorder (PTSD) following positive feedback from the U.S. FDA. Final data from the phase II Attune study showed that BNC-210 improved PTSD symptom severity at week 12 with efficacy observed as early as week four.
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Cervomed analyzing data after phase IIb miss in Lewy body dementia

Dec. 10, 2024
By Jennifer Boggs
Cervomed Inc. executives said they intend to scrutinize low plasma drug concentrations that appeared to spoil results from the phase IIb Rewind-LB trial testing neflamapimod in patients with dementia with Lewy bodies.
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Cstone’s ROR1 ADC chases Merck’s, plus China biotech data: ASH 24

Dec. 10, 2024
By Marian (YoonJee) Chu
Four Chinese biopharmaceuticals unveiled early data on respective cancer therapies at the American Society of Hematology (ASH) 2024 meet in San Diego, including Cstone Pharmaceuticals Co. Ltd.’s receptor tyrosine kinase-like orphan receptor 1 (ROR1)-inhibiting antibody-drug conjugate (ADC) in phase I study for lymphomas.
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US lawmakers launch year-end push for PBM reforms

Dec. 10, 2024
By Mari Serebrov
If a bipartisan group of U.S. House members has its way, at least some of the legislation congressional committees have passed to target pharmacy benefit manager (PBM) practices could yet make it into law this year. That is if congressional leaders listen to the rank-and-file members.
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