By looking for a combination of DNA and protein biomarkers, a single experimental blood test could detect eight different cancers, and identify the anatomical location of the majority of tumors it detected.
According to the World Health Organization's (WHO's) Global tuberculosis report 2017, "TB is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, ranking above HIV/AIDS. In 2016, there were an estimated 1.3 million TB deaths among HIV-negative people . . . and an additional 374,000 deaths among HIV-positive people. An estimated 10.4 million people fell ill with TB in 2016."
Aging is a major risk factor in most diseases. But much remains to be learned about how aging itself and age-associated diseases are coupled at the molecular level. Researchers from the Salk Institute for Biological Studies have identified a molecular link between aging and dementia through studies of the experimental compound J-147.
Immunological memory was once considered the sole provenance of the adaptive immune system's T and B cells, while the adaptive immune system "was thought to respond in the same naïve way every time," Niels Riksen told BioWorld.
Staphylococcus aureus’ role as a human pathogen may present a headache for gene editing. Looking at blood samples from human donors, researchers found that the majority of samples had pre-existing antibodies to the Cas9 from both S. aureus and Streptococcus pyogenes.
Treating mice with tungsten salt could reduce the numbers of Enterobacteriaceae specifically under the anaerobic conditions that are typical of inflammation, and reduced the symptoms of mice with colitis.
