Researchers reported data today that run counter to a major tenet of neural regeneration after injury, namely that the so-called glial scar inhibits axons from regrowing and reconnecting with their targets.
One of the prospects of nanotechnology is to minimize toxicity through the precise delivery of therapeutics to where they are needed, which enables the delivery of highly toxic agents only to those cells where they are needed.
Among the insights to be had from the "minimal genome" cell that was reported Thursday is just how relative the term minimal is – a fact freely acknowledged by its creators.
In work that has implications for melanoma, targeting cancer metabolism and noncoding RNAs, researchers have reported that a broad swath of melanomas were addicted to the long intergenic noncoding RNA (lincRNA) SAMMSON.
Researchers from Gilead Sciences Inc., with colleagues from academia, have identified the mechanism by which a major protein of the hepatitis B virus (HBV) promotes transcription of viral DNA – a finding that could lead to new drug targets.
Researchers have developed a so-called human challenge model for dengue vaccine, and used it to test a vaccine that was shown to evoke an immune response to all four strains of dengue virus, and protect against subsequent infection with serotype 2, which has been the most challenging serotype from a vaccine development standpoint.