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BioWorld - Monday, February 16, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

Biocom 2024 panel

Biocom 2024: Developing new AI capabilities (and maybe going faster, too)

Feb. 28, 2024
By Brian Orelli
Biocom California’s Global Life Science Partnering & Investor Conference kicked off with a panel discussion focused on artificial intelligence (AI) in drug discovery. While there’s been a lot of hype over how AI and machine learning have the potential to help companies speed up drug development, panelists hypothesized the largest opportunities are in developing new capabilities, potentially increasing the success rate going from discovery to regulatory approval.
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Bridgene nabs Galapagos in a $700M multitarget oncology discovery deal

Jan. 4, 2024
By Brian Orelli
Following up on a 2021 partnership with Takeda Pharmaceutical Co. Ltd., Bridgene Biosciences Inc. has signed up a second international drug company, Galapagos NV, to use its chemoproteomic platform, IMTAC (Isobaric Mass Tagged Affinity Characterization), to discover small-molecule drug candidates.
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ASH 2023: Multiple new dosing regimens for multiple myeloma

Dec. 12, 2023
By Brian Orelli
Multiple studies at the 65th American Society of Hematology Annual Meeting 2023 have the potential to change the treatment paradigm for first-line treatment of multiple myeloma.
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ASH 2023: Syndax makes splash in cGVHD and leukemia

Dec. 12, 2023
By Brian Orelli
It’s not every day you see a small drug company’s presentations get picked for both the plenary session and the late-breaker session at a conference, but Syndax Pharmaceuticals Inc. managed to do just that at the 65th American Society of Hematology Annual Meeting 2023 – with a little help from a friend.
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CAR T cell with implanted gene strand

ASH 2023: CAR T therapies take on autoimmune diseases

Dec. 11, 2023
By Brian Orelli
CAR T-cell therapies have worked well at curing blood malignancies, but a group out of the University Hospital of Erlangen have repurposed the technology as a treatment for autoimmune diseases. The expansion into new diseases has required cooperation between multiple departments, with CAR T experts taking the lead on treatment and potential side effects, and rheumatologists measuring the outcomes of the treatment.
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Biocom space-panel

Biocom 2023: There’s science going on 250 miles above your head

March 7, 2023
By Brian Orelli
Performing experiments and potentially manufacturing products in space offers some unique advantages in a near-zero gravity environment. Space changes buoyancy, hydrostatic pressure and convective heat flow. Researchers are studying how those changes affect cells, but also looking to take advantage of the changes to create products in manufacturing processes that wouldn’t be possible on earth.
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Biocom pic 1 3-3

Biocom 2023: Venture capitalists spill the beans

March 3, 2023
By Brian Orelli
According to venture capitalists on three different panels at Biocom California’s Global Life Science Partnering & Investor Conference, there’s still money available for newcos looking to get started. But the pitch they’re going to have to make to VCs is a little different than what would have worked a few years ago.
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Biocom-1-pic.png

Biocom 2023: Pharma’s wants and needs in the new market environment

March 2, 2023
By Brian Orelli
During two different panels at Biocom California’s Global Life Science Partnering & Investor Conference, executives from a variety of pharmaceutical companies laid out their wants and needs in the current market environment. Large drug companies have relied on biotech companies to build out their pipelines for many years, but the level of outside inventions has been increasing over the last few years.
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Biocom space-panel
Drug Design, Drug Delivery & Technologies

Biocom 2023: There’s science going on 250 miles above your head

March 2, 2023
By Brian Orelli
Performing experiments and potentially manufacturing products in space offers some unique advantages in a near-zero gravity environment. Space changes buoyancy, hydrostatic pressure and convective heat flow. Researchers are studying how those changes affect cells, but also looking to take advantage of the changes to create products in manufacturing processes that wouldn’t be possible on earth.
Read More
Biocom space-panel

Biocom 2023: There’s science going on 250 miles above your head

March 1, 2023
By Brian Orelli
Performing experiments and potentially manufacturing products in space offers some unique advantages in a near-zero gravity environment. Space changes buoyancy, hydrostatic pressure and convective heat flow. Researchers are studying how those changes affect cells, but also looking to take advantage of the changes to create products in manufacturing processes that wouldn’t be possible on earth.
Read More
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