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BioWorld - Monday, April 6, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

Cell research illustration
Immune

What immunology can learn from oncology

Oct. 18, 2024
By Brian Orelli
During an Innovation Ignited webinar sponsored by Johnson & Johnson, experts talked about how precision medicine has helped advance the field of oncology and how those lessons can be applied to immunology. Advancements in precision medicine have helped oncologists know which drugs are most likely to help patients as their tumors advance and mutate.
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Cell research illustration

What immunology can learn from oncology

Oct. 17, 2024
By Brian Orelli
During an Innovation Ignited webinar sponsored by Johnson & Johnson, experts talked about how precision medicine has helped advance the field of oncology and how those lessons can be applied to immunology.
Read More
Handshake with tech background
Respiratory

Generate:Biomedicines signs up Novartis to $1B+ multitarget deal

Sep. 27, 2024
By Brian Orelli
Novartis AG is enlisting the help of Generate:Biomedicines Inc. and its artificial intelligence platform to generate drugs for multiple undisclosed targets. The number of targets and therapeutic areas also weren’t disclosed. Novartis will pick the targets, although the targets Generate has been working on are off limits. Generate will be responsible for creating the lead candidate, at which point Novartis will take over development.
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Handshake with tech background

Generate:Biomedicines signs up Novartis to $1B+ multitarget deal

Sep. 24, 2024
By Brian Orelli
Novartis AG is enlisting the help of Generate:Biomedicines Inc. and its artificial intelligence platform to generate drugs for multiple undisclosed targets. The number of targets and therapeutic areas also weren’t disclosed. Novartis will pick the targets, although the targets Generate has been working on are off limits. Generate will be responsible for creating the lead candidate, at which point Novartis will take over development.
Read More

AACR: Cancer deaths declining, but more funding needed

Sep. 18, 2024
By Brian Orelli
Scientists and doctors are getting much better at developing treatments for cancer. More than 18 million people with a history of cancer were alive in the U.S. at the beginning of 2022, up from just 3 million in 1971, according to the 14th edition of the American Association for Cancer Research (AACR) Cancer Progress Report. And that number is expected to rise to 26 million by 2040.
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Doctor and patient consultation

The massive, untapped opportunity in women’s health

Sep. 16, 2024
By Brian Orelli
Biocom California’s most recent edition of its Let's Talk About series covered the future of women’s health. The panel of executives from companies and investors in women’s health were frustrated about the state of funding for the space. “Only about 1% of health care R&D dollars go [specifically] to women’s health outside of oncology,” Jenn Kiang, director of corporate affairs and development at Daré Bioscience Inc. told the audience. But the opportunity is huge, she said.
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Adenovirus cells
Immuno-oncology

Vironexis exits stealth with 10+ AAV-delivered immuno-oncology candidates

Sep. 13, 2024
By Brian Orelli
Vironexis Biotherapeutics Inc. has come out of stealth mode, disclosing that it has more than 10 product candidates it’s been developing over the last three years. The therapies are built on the company’s AAV-based platform, Transjoin, which is designed to have patients' livers express bispecific antibodies that bind to both CD3 on T-cells and various targets on tumor cells.
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Adenovirus cells
Newco news

Vironexis exits stealth with 10+ AAV-delivered immuno-oncology candidates

Sep. 12, 2024
By Brian Orelli
Vironexis Biotherapeutics Inc. came out of stealth mode today, disclosing that it has more than 10 product candidates it’s been developing over the last three years. The therapies are built on the company’s AAV-based platform, Transjoin, which is designed to have patients' livers express bispecific antibodies that bind to both CD3 on T-cells and various targets on tumor cells.
Read More
Immune

Candid launches with bispecific antibodies and $370M in hand

Sep. 10, 2024
By Brian Orelli
Candid Therapeutics Inc. launched with ex-China control of two bispecific T-cell engager antibodies that it plans to develop for autoimmune diseases. The San Diego-based company will start off with a pocketful of cash, having raised over $370 million for the development of the in-licensed candidates.
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Red rocket launch button on keyboard
Newco news

Candid launches with bispecific antibodies and $370M in hand

Sep. 9, 2024
By Brian Orelli
Candid Therapeutics Inc. launched with ex-China control of two bispecific T-cell engager antibodies that it plans to develop for autoimmune diseases. The San Diego-based company will start off with a pocketful of cash, having raised over $370 million for the development of the in-licensed candidates.
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