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BioWorld - Monday, March 30, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

CRISPR Cas9 illustration
Cancer

Azalea exits stealth to develop its in vivo gene engineering technology

Nov. 10, 2025
By Brian Orelli
No Comments
San Francisco Bay Area researchers from UC Berkeley, UC San Francisco and Stanford University have combined their technologies to create Azalea Therapeutics Inc., a company focused on editing cells in vivo.
Read More
CRISPR Cas9 illustration
Newco news

Azalea exits stealth to develop its in vivo gene engineering technology

Nov. 6, 2025
By Brian Orelli
No Comments
San Francisco Bay Area researchers from UC Berkeley, UC San Francisco and Stanford University have combined their technologies to create Azalea Therapeutics Inc., a company focused on editing cells in vivo.
Read More
Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Cancer

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 6, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors. The biotech got a leg up on development from its principal investor, Korean biotech ABL Bio Inc., where the discovery work was accomplished.
Read More
Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Newco news

Neok Bio launches with $75M to develop bispecific ADCs

Nov. 5, 2025
By Brian Orelli
No Comments
Neok Bio Inc. was formed earlier this year and is already on schedule to file an IND in a few months for its two bispecific antibody-drug conjugates (ADCs) to treat various types of tumors.
Read More
Thymus illustration
Immune

Zag Bio launches with $80M to dampen immune response via thymus

Oct. 29, 2025
By Brian Orelli
No Comments
Zag Bio Inc. came out of stealth mode with $80 million in funding so far, including a recently closed series A financing, to develop its platform for autoimmune diseases using drugs targeted to the thymus where thymic regulatory cells are produced.
Read More
Thymus illustration
Newco news

Zag Bio launches with $80M to dampen immune response via thymus

Oct. 28, 2025
By Brian Orelli
No Comments
Zag Bio Inc. came out of stealth mode with $80 million in funding so far, including a recently closed series A financing, to develop its platform for autoimmune diseases using drugs targeted to the thymus where thymic regulatory cells are produced.
Read More
Drug R&D concept image.
Drug design, drug delivery & technologies

Flagship Pioneering launches Expedition to advance covalent-binding drugs

Oct. 23, 2025
By Brian Orelli
No Comments
Expedition Medicines, which Flagship Pioneering Inc. has incubated for the past three years, came out of stealth mode with a $50 million commitment from Flagship to support Expedition’s platform technology to discover small molecules that covalently bind to their target.
Read More
Drug R&D concept image.
Newco news

Flagship Pioneering launches Expedition to advance covalent-binding drugs

Oct. 22, 2025
By Brian Orelli
No Comments
Expedition Medicines, which Flagship Pioneering Inc. has incubated for the past three years, came out of stealth mode with a $50 million commitment from Flagship to support Expedition’s platform technology to discover small molecules that covalently bind to their target.
Read More
Mast cell releasing histamine during allergic response
Immune

Excellergy launches with $70M for a new class of allergy drugs

Oct. 16, 2025
By Brian Orelli
No Comments
With $70 million in hand, Excellergy Inc. is ready to advance its lead candidate for allergic diseases into clinical trials. The series A round was led by Samsara Biocapital with co-investments from Red Tree Venture Capital and Decheng Capital.
Read More
Mast cell releasing histamine during allergic response

Excellergy launches with $70M for a new class of allergy drugs

Oct. 13, 2025
By Brian Orelli
No Comments
With $70 million in hand, Excellergy Inc. is ready to advance its lead candidate for allergic diseases into clinical trials. The series A round was led by Samsara Biocapital with co-investments from Red Tree Venture Capital and Decheng Capital.
Read More
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