Huazhong University of Science and Technology and affiliated organizations have explored the role of microRNA-218-5p (miR-218-5p) in Parkinson’s disease (PD).
The σ2 receptor (σ2R) has been recently identified as transmembrane protein 97 (TMEM97), and ligands of σ2R/TMEM97 have previously shown the ability to alleviate mechanical hypersensitivity in mouse models of neuropathic pain.
CD38 is the main NAD+-hydrolyzing enzyme, and it also catabolizes nicotinamide mononucleotide (NMN) and other extracellular NAD+ precursors prior to their intracellular transport for NAD+ biosynthesis.
Colorectal cancer (CRC) is a heterogeneous malignancy that starts with the sequential transformation of normal mucosa to adenoma and finally to carcinoma, when it attains metastatic potential. The most frequent metastatic site in CRC is the liver. Researchers from Nanjing Medical University and collaborators identified a significant overexpression of procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3) in liver metastasis tissue samples.
Researchers from Third Military Medical University of the Chinese PLA have published data from a study that aimed to investigate the biological functions and molecular mechanisms of tandem C2 domains, nuclear (TC2N) in the development and progression of breast cancer.
