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The neurodevelopmental disorder MECP2 duplication syndrome (MDS) is caused by duplications spanning the methyl-CpG binding protein 2 gene (MECP2) locus, and researchers have shown that the MDS-like phenotype can be reversed in adult symptomatic mice using MECP2-specific antisense oligonucleotides (MECP2-ASOs).
Keeping you up to date on recent developments in oncology, including: NCI team devises method to recruit myeloid cells in pushback against cancer; Algorithm ranks cancer therapies for efficacy; New twist on quantum dots could revolutionize imaging.
A study led by Chinese scientists at Tsinghua University in Beijing has demonstrated that the gut microbial metabolite butyrate can directly modulate the antitumor CD8 "killer" T-cell response and improve chemotherapy efficacy through ID2-dependent IL-12 signaling.
Keeping you up to date on recent developments in cardiology, including: Algorithms can distinguish varying grades of pulmonary edema in heart failure; Cholesterol-independent heart disease risk gene; Study confirms role of smoking in CAD among Blacks.
The animal world is full of species that can perform astonishing, and sometimes disgusting, feats. Take vultures, for example. “They eat this rotten meat that is full of pathogens and toxins, and they stay healthy,” Neta Raab told BioWorld. Raab is the co-founder and CEO of Wild Biotech Ltd., an Israeli startup that is seeking to understand gut microbiome contributions to these animal superpowers, and harness them for therapeutic use.
Keeping you up to date on recent developments in neurology, including: New discovery improves DBS effects in Parkinson’s; Women accumulate Alzheimer’s-related protein faster; Brain cell alcohol metabolism affects behavior, addiction; Lipopolysaccharides induce neural repair sweet spot.
Investigators at the department of neuroscience at the faculty of health and medical sciences at the University of Copenhagen have discovered the mechanism of action of a synthetic cannabinoid derivative on spinal astrocytes for reduction of pathological tremors.
Keeping you up to date on recent developments in diagnostics, including: Review highlights differences in accuracy of COVID-19 rapid tests; Likelihood of disease from hidden genetic defects; Confocal PET enables color differentiation of PET tracers in preclinical imaging.
The animal world is full of species that can perform astonishing, and sometimes disgusting, feats. Take vultures, for example. “They eat this rotten meat that is full of pathogens and toxins, and they stay healthy,” Neta Raab told BioWorld. Raab is the co-founder and CEO of Wild Biotech Ltd., an Israeli startup that is seeking to understand gut microbiome contributions to these animal superpowers, and harness them for therapeutic use.
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